Page 67 - MI-2-4

Microbes & Immunity Management of obesity

food intake and increased risk of obesity: A narrative review. 99. Beam A, Clinger E, Hao L. Effect of diet and dietary
Foods. 2024;13:2627. components on the composition of the gut microbiota.
Nutrients. 2021;13:2795.
doi: 10.3390/foods13162627
doi: 10.3390/nu13082795
89. Heindel JJ, Lustig RH, Howard S, Corkey BE. Obesogens:
A unifying theory for the global rise in obesity. Int J Obes 100. Borrego-Ruiz A, Borrego JJ. Human gut microbiome, diet,
(Lond). 2024;48:449-460. and mental disorders. Int Microbiol. 2025;28(1):1-15.
doi: 10.1038/s41366-024-01460-3 doi: 10.1007/s10123-024-00518-6
90. Flier JS. Moderating “the great debate”: The carbohydrate- 101. Nagpal R, Neth BJ, Wang S, Craft S, Yadav H. Modified
insulin vs. The energy balance models of obesity. Cell Metab. mediterranean-ketogenic diet modulates gut microbiome
2023;35:737-741. and short-chain fatty acids in association with alzheimer’s
disease markers in subjects with mild cognitive impairment.
doi: 10.1016/j.cmet.2023.03.020
EBioMedicine. 2019;47:529-542.
91. Poti JM, Braga B, Qin B. Ultra-processed food intake and
obesity: What really matters for health-processing or doi: 10.1016/j.ebiom.2019.08.032
nutrient content? Curr Obes Rep. 2017;6:420-431. 102. Bamal A, Goley R, Garg AP. Health managements through
gut microbiota. Am J Biomed Sci Res. 2025;25(5):700-727.
doi: 10.1007/s13679-017-0285-4
doi: 10.34297/AJBSR.2025.25.003368
92. Wu GD, Chen J, Hoffmann C, et al. Linking long-term
dietary patterns with gut microbial enterotypes. Science. 103. Koh A, Molinaro A, Ståhlman M, et al. Microbially produced
2011;334:105-108. imidazole propionate impairs insulin signaling through
mTORC1. Cell. 2018;175:947-961.e17.
doi: 10.1126/science.1208344
doi: 10.1016/j.cell.2018.09.055
93. Brinkworth GD, Noakes M, Clifton PM, Bird AR.
Comparative effects of very low-carbohydrate, high-fat and 104. Liu Y, Dai M. Trimethylamine N-Oxide generated by the
highcarbohydrate, low-fat weight-loss diets on bowel habit gut microbiota is associated with vascular inflammation:
and faecal short-chain fatty acids and bacterial populations. New insights into atherosclerosis. Mediators Inflamm.
Br J Nutr. 2009;101:1493-1502. 2020;2020:4634172.
doi: 10.1017/S0007114508094658 doi: 10.1155/2020/4634172
94. Duncan SH, Belenguer A, Holtrop G, Johnstone AM, 105. Schicho R, Marsche G, Storr M. Cardiovascular
Flint HJ, Lobley GE. Reduced dietary intake of carbohydrates complications in inflammatory bowel disease. Curr Drug
by obese subjects results in decreased concentrations of Targets. 2015;16:181-188.
butyrate and butyrate-producing bacteria in feces. Appl doi: 10.2174/1389450116666150202161500
Environ Microbiol. 2007;73:1073-1078.
106. Beyaz Coşkun A, Sağdiçoğlu Celep AG. Therapeutic
doi: 10.1128/AEM.02340-06
modulation methods of gut microbiota and gut-liver axis.
95. David LA, Maurice CF, Carmody RN, et al. Diet rapidly Crit Rev Food Sci Nutr. 2021;62(23):6505-6515.
and reproducibly alters the human gut microbiome. Nature. doi: 10.1080/10408398.2021.1902263
2014;505:559-563.
107. Hu H, Lin A, Kong M, et al. Intestinal microbiome and
doi: 10.1038/nature12820
nafld: Molecular insights and therapeutic perspectives.
96. Zimmer J, Lange B, Frick JS, et al. A vegan or vegetarian diet J Gastroenterol. 2020;55(2):142-158.
substantially alters the human colonic faecal microbiota. Eur doi: 10.1007/s00535-019-01649-8
J Clin Nutr. 2012;66:53-60.
108. Bisht N, Garg AP. Role of gut microbiota in human health.
doi: 10.1038/ejcn.2011.141
Res J Biotech. 2021;16(1):202-212.
97. Sidhu SRK, Kok CW, Kunasegaran T, Ramadas A. Effect of 109. Yadav H, Lee JH, Lloyd J, Walter P, Rane SG. Beneficial
plant-based diets on gut microbiota: A systematic review of metabolic effects of a probiotic Via butyrate-induced glp-1
interventional studies. Nutrients. 2023;15:1510.
hormone secretion. J Biol Chem. 2013;288(35):25088-25097.
doi: 10.3390/nu15061510
doi: 10.1074/jbc.M113.452516
98. Clemente-Suárez VJ, Beltrán-Velasco AI, Redondo-Flórez L, 110. Rajkumar H, Mahmood N, Kumar M, Varikut SR, Challa HR,
Martín-Rodríguez A, Tornero-Aguilera JF. Global impacts Myakala SP. Effect of probiotic (Vsl#3) and omega-3 on lipid
of western diet and its effects on metabolism and health: profile, insulin sensitivity, inflammatory markers, and gut
A narrative review. Nutrients. 2023;15:2749.
colonization in overweight adults: A randomized, controlled
doi: 10.3390/nu15122749 trial. Mediators Inflamm. 2014;2014:348959.

Volume 2 Issue 4 (2025) 59 doi: 10.36922/MI025160036