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Tumor Discovery                                                                    Adult cystic hyroma




            Table 1. Classification of lymphatic malformations based on   Availability of data
            anatomical location
                                                               Not applicable.
             Class            Description
            Stage I          Unilateral Infrahyoid lesion      References
            Stage II         Unilateral Suprahyoid lesion      1.   Gow L, Gulati R, Khan A, et al., 2011, Adult-onset cystic
            Stage III        Unilateral Suprahyoid and Infrahyoid lesion  hygroma: A case report and review of management. Grand
                                                                  Rounds, 11: 5–11.
            Stage IV         Bilateral Suprahyoid lesion
                                                                  https://doi.org/10.1102/1470-5206.2011.0002
            Stage V          Bilateral Suprahyoid and Infrahyoid lesion
                                                               2.   Suk S, Sheridan M, Saenger JS, 1997, Adult lymphangioma:
                                                                  A case report. Ear Nose Throat J, 76(12): 881–883.
            cases, alternative procedures, such as sclerotherapy with
            tetracycline,  bleomycin,  and  triamcinolone  or  drainage,   3.   Bloom DC, Perkins JA, Manning SC, 2004, Management of
            have been recommended. The next therapeutic treatment   lymphatic malformations. Curr Opin Otolaryngol Head Neck
            option is radiofrequency ablation . OK-432 (Picibanil),   Surg, 12(6): 500–4.
                                       [21]
            a sclerosing agent recommended by Ogita  et  al. , was      https://doi.org/10.1097/01.moo.0000143971.19992.2d
                                                    [32]
            prepared by incubating streptococcal pyogenes with   4.   Naidu SI, McCalla MR, 2004, Lymphatic malformations of
            penicillin [33,34] . It is used to perform sclerosis in cystic   the head and neck in adults: A case report and review of the
            lesions of the neck as it has a property of inducing fibrosis   literature. Ann Otol Rhinol Laryngol., 113(3 Pt 1): 218–222.
            secondary to inflammatory and cicatricle changes with the      https://doi.org/10.1177/000348940411300309
            consequent contraction of the lymphangioma.
                                                               5.   Schefter RP, Olsen KD, Gaffey TA, 1985, Cervical
            4. Conclusion                                         lymphangioma in the adult.  Otolaryngol Head Neck Surg,
                                                                  93(1): 65–69.
            Although cystic hygroma is rare in adults, differential
            diagnosis among all cervical lymphangiomas is necessary.      https://doi.org/10.1177/019459988509300113
            Surgical excision is the gold standard for the treatment   6.   Antoniades K, Kiziridou A, Psimopoulou M, 2000,
            of cystic hygroma, except in complex cases, while     Traumatic cervical cystic hygroma. Int J Oral Maxillofacial
            histopathology is the definitive diagnostic modality.  Surg, 29(1): 47–48.
            Acknowledgments                                    7.   Brea-Álvarez B, Roldan-Fidalgo A, 2015, Quistes en el
                                                                  triángulo cervical posterior en adultos [Cysts in the posterior
            None.                                                 triangle of the neck in adults]. Acta Otorrinolaringol Esp,
                                                                  66(2): 106–110.
            Funding                                               https://doi.org/10.1016/j.otorri.2014.02.013

            All authors declare that there is no financial support   8.   Curran AJ, Malik N, McShane D,  et al., 1996, Surgical
            received from any organization for the submitted work.  management of lymphangiomas in adults. J Laryngol Otol,
                                                                  110(6): 586–589.
            Conflict of interest
                                                                  https://doi.org/10.1017/s0022215100134334
            The authors declare that they have no conflict of interests.   9.   Farmand M, Kuttenberger JJ, 1996, A new therapeutic
            All authors declare that they have no financial relationships   concept for the treatment of cystic hygroma. Oral Surg Oral
            at present or within the previous 3  years with any   Med Oral Pathol Oral Radiol Endod, 81(4): 389–395.
            organizations that might have an interest in the submitted
            work and have no other relationships or activities that      https://doi.org/10.1016/s1079-2104(96)80013-8
            could appear to have influenced the submitted work.  10.  Filston HC, 1994, Hemangiomas, cystic hygromas, and
                                                                  teratomas of the head and neck. Semin Pediatr Surg, 3(3):
            Ethics approval and consent to participate            147–159.
            Informed consent was obtained from the patient for being   11.  Kennedy TL, Whitaker M, Pellitteri P, Wood WE, 2001,
            included in this study.                               Cystic hygroma/lymphangioma: a rational approach to
                                                                  management. Laryngoscope, 111(11): 1929–1937.
            Consent for publication                            12.  Rajendran R, Sivapathasundaram B, 2009, Shafer’s Textbook
                                                                                 th
            Informed consent to publish this case was obtained from   of Oral Pathology. 6  ed. New Delhi, India: Elsevier.
            the patient.                                       13.  Teresa MO, Rickert SM, Diallo AM, et al., 2013, Lymphatic



            Volume 1 Issue 2 (2022)                         4                       https://doi.org/10.36922/td.v1i2.151
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