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obtained. Protocols and procedures for new methods must be included in detail for the reproducibility of the experiments. Informed
consent should be obtained from patients or parents before the experiments start and should be mentioned in this section. For human
and/or research, research ethics information, such as ethics approval identifiers and the name of Institutional Ethics Review Board
or Institutional Review Board, should be indicated in this section.
• This section focuses on the results and findings of the experiments performed. After (statistical) analysis, all results, including tables
and figures, must be neatly presented. If necessary, this section can be sub-divided into multiple topical sub-sections.
• This section should provide the significance of the results and identify the impact of the research in a broader context. It should not
be redundant or similar to the content of the results section.
• Use this section for interpretation only, and not to summarize information already presented in the text or abstract.

It is acceptable to merge both Results and Discussion as a single section.

Data and image processing
Post-acquisition processing of images, photos and figures should be kept minimum to ensure that the final figures accurately reflect the original
data as it was captured and/or produced. Any alterations should be applied to the entire image. Any kind of alteration, including but not limited
to brightness, contrast and color balance, has to be clearly stated in the figure legend and in Materials and Methods section. For simulated or
model figures, the software used for production, editing, and/or processing should be mentioned. Presenting images in the same figure must
be made apparent and should be explicitly indicated in the appropriate figure legends.
Data comparisons should only be made from comparative experiments (or data from the same experiment). Same piece of data or figure
should not be used in multiple instances, unless the images/data describe different aspects of the same experiment (reasons must be stated,
wherever appropriate, in this regard). If inappropriate image/data manipulation is identified after publication, the editors reserve the right to ask
for the original data and, if that is not satisfactory, to issue a correction or retract the paper, as appropriate.

Unit of measurements
Use SI units.

Nomenclature of genus and species

Write in italics (e.g. Escherichia coli). The full genus and species names must be mentioned both in the manuscript title at the first appearance
of an organism in an article. The abbreviation (e.g. E. coli) is allowed after first mention.

Nomenclature of genes, mutations, genotypes, and alleles
Write in italics. Tumor Discovery highly encourages the use the recommended names found in the gene nomenclature databases, for
instance, HUGO Gene Nomenclature Committee.

Chemical compounds
Tumor Discovery requires authors to fulfill the requirements below while reporting and/or describing a chemical compound in articles:

Scenario Requirements
Naming chemical compounds Use either IUPAC conventions or common names such as cholesterol and
cephalosporins
Reporting a new chemical compound Provide the exact structure of the compound as well as sufficient data regarding the
purity and identity of the compound
Reporting the use of a known chemical Provide sufficient data regarding the source, purity and identity of the compound
compound

Figures
Include all figures, including photographs, scanned images, graphs, charts and schematic diagrams, at the back of manuscript. Avoid
unnecessary decorative effects (e.g., 3D graphs) and minimize image processing (e.g., changes in brightness and contrast applied uniformly
for the entire figure should be avoided or minimized). All images should be set against white background.

All figures should be numbered (e.g., Figure 1, Figure 2) in boldface. Label all figures (e.g., axis, structures), and add caption (a brief title) and
legend as a description of the illustration below each figure. Explain all symbols and abbreviations used. Each figure should have a brief title
(also known as caption) that describes the entire figure without citing specific panels, followed by a legend, which is either the description of
each panel or further description about the single image. Identify each panel with uppercase letters in parenthesis (e.g. (A), (B), (C), etc.)
Figures must be cited in chronological manner in the text.