Page 22 - TD-3-3
P. 22

Tumor Discovery                                                    Immune and epigenetic therapies for TNBC



               chemotherapy-treated triple-negative breast cancer patients.   via regulating TIMP2-MMP-2/-9 pathway. Am J Cancer Res.
               NPJ Breast Cancer. 2016;2(1):16033.                2018;8:422-434.
               doi: 10.1038/npjbcancer.2016.33                 74.  Yang H, Salz T, Zajac-Kaye M, Liao D, Huang S, Qiu Y.
                                                                  Overexpression of  histone deacetylases  in cancer  cells
            63.  Noy R, Pollard JW. Tumor-associated macrophages: From
               mechanisms to therapy. Immunity. 2014;41:49-61.    is controlled by interplay of transcription factors and
                                                                  epigenetic modulators. FASEB J. 2014;28(10):4265-4279.
               doi: 10.1016/j.immuni.2014.06.010
                                                                  doi: 10.1096/fj.14-250654
            64.  Hollmén M, Karaman S, Schwager S,  et al. G-CSF
               regulates macrophage phenotype and associates with poor   75.  Title AC, Silva PN, Godbersen S, Hasenöhrl L, Stoffel M. The
               overall survival in human triple-negative breast cancer.   miR-200-Zeb1 axis regulates key aspects of β-cell function
               Oncoimmunology. 2016;5(3):e1115177.                and survival in vivo. Mol Metab. 2021;53:101267.
                                                                  doi: 10.1016/j.molmet.2021.101267
               doi: 10.1080/2162402X.2015.1115177
            65.  Jamiyan T, Kuroda H, Yamaguchi R, Abe A, Hayashi M.   76.  Miller TE, Ghoshal K, Ramaswamy B,  et al.
               CD68- and CD163-positive tumor-associated macrophages   MicroRNA-221/222  confers  tamoxifen  resistance
               in triple negative cancer of the breast.  Virchows Arch.   in breast cancer by targeting p27Kip1.  J  Biol Chem.
               2020;477:767-775.                                  2008;283(44):29897-29903.
               doi: 10.1007/s00428-020-02855-z                    doi: 10.1074/jbc.M804612200
            66.  Wang  J,  Chen  H,  Chen  X,  Lin  H.  Expression  of  tumor-  77.  Zhang Z,  Zhou C,  Li  X,  et al. Loss of  CHD1  promotes
               related macrophages and cytokines after surgery of triple-  heterogeneous mechanisms of resistance to AR-targeted
               negative breast cancer patients and its implications. Med Sci   therapy via chromatin dysregulation.  Cancer  Cell.
               Monit. 2016;22:115-120.                            2020;37(4):584-598.e11.
               doi: 10.12659/msm.895386                           doi: 10.1016/j.ccell.2020.03.001
            67.  Niu M, Valdes S, Naguib YW, Hursting SD, Cui Z. Tumor-  78.  Cortazar P, Zhang L, Untch M, et al. Pathological complete
               associated macrophage-mediated targeted therapy of triple-  response and long-term clinical benefit in breast cancer: The
               negative breast cancer. Mol Pharm. 2016;13(6):1833-1842.  CTNeoBC pooled analysis. Lancet. 2014;384(9938):164-172.
               doi: 10.1021/acs.molpharmaceut.5b00987             doi: 10.1016/S0140-6736(13)62422-8
            68.  Rogers  TL,  Holen  I.  Tumour  macrophages  as  potential   79.  Kagihara JA, Andress M, Diamond JR. Nab-paclitaxel
               targets of bisphosphonates. J Transl Med. 2011;9:177.  and atezolizumab for the treatment of PD-L1-positive,
                                                                  metastatic triple-negative breast cancer: Review and future
               doi: 10.1186/1479-5876-9-177                       directions. Expert Rev Precis Med Drug Dev. 2020;5(2):59.
            69.  Yang Q, Guo N, Zhou Y, Chen J, Wei Q, Han M. The role      doi: 10.1080/23808993.2020.1730694
               of  tumor-associated  macrophages  (TAMs)  in  tumor
               progression and relevant advance in targeted therapy. Acta   80.  Adams S, Schmid P, Rugo HS,  et al. Pembrolizumab
               Pharm Sin B. 2020;10:2156-2170.                    monotherapy  for  previously  treated  metastatic  triple-
                                                                  negative breast cancer: Cohort A of the phase II
               doi: 10.1016/j.apsb.2020.04.004                    KEYNOTE-086 study. Ann Oncol. 2019;30(3):397-404.
            70.  Panjarian S, Issa JPJ. The roles of DNA demethylases in      doi: 10.1093/annonc/mdy517
               triple-negative  breast  cancer.  Pharmaceuticals  (Basel).
               2021;14:628.                                    81.  Ozaki Y, Matsumoto K, Takahashi M, et al. Phase II study
                                                                  of a combination therapy of nivolumab, bevacizumab and
               doi: 10.3390/ph14070628
                                                                  paclitaxel in patients with HER2-negative metastatic breast
            71.  Malpeli G, Innamorati G, Decimo I,  et al. Methylation   cancer as a first-line treatment (WJOG9917B, NEWBEAT
               dynamics  of  RASSF1A  and its  impact  on  cancer.  Cancers   trial). J Clin Oncol. 2018;36(15_suppl):TPS1110.
               (Basel). 2019;11:959.                              doi: 10.1016/j.ejca.2022.05.014
               doi: 10.3390/cancers11070959                    82.  Chen F, Chen N, Gao Y, Jia L, Lyu Z, Cui J. Clinical progress
            72.  Saelee P, Pongtheerat T. APC promoter hypermethylation as   of PD-1/L1 inhibitors in breast cancer immunotherapy.
               a prognostic marker in breast cancer patients. Asian Pac J   Front Oncol. 2022;11:724424.
               Cancer Prev. 2020;21(12):3627-3632.
                                                                  doi: 10.3389/fonc.2021.724424
               doi: 10.31557/APJCP.2020.21.12.3627             83.  Li Y, Zhang H, Merkher Y,  et al. Recent advances in
            73.  Chien YC, Liu LC, Ye HY, Wu JY, Yu YL. EZH2 promotes   therapeutic  strategies  for  triple-negative  breast  cancer.
               migration and invasion of triple-negative breast cancer cells   J Hematol Oncol. 2022;15:121.


            Volume 3 Issue 3 (2024)                         16                                doi: 10.36922/td.3383
   17   18   19   20   21   22   23   24   25   26   27