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Tumor Discovery Expert consensus of NUT carcinoma

tumors with NUT rearrangement, which began in 2022. individuals were involved in this paper’s editorial or peer-
From June 2023 to April 2024, we diagnosed and treated review process, either directly or indirectly. In addition, the
80 cases of NUT carcinoma. However, due to insufficient other authors declare that they have no known competing
awareness among most physicians and the high rate of financial interests or personal relationships that could have
misdiagnoses, the actual number of NUT carcinoma influenced the work reported in this paper.
cases could be much higher. To address these issues, we
collaborated with multidisciplinary experts from various Author contributions
countries to establish an international platform to increase Conceptualization: Zhuomiao Ye, Xin Li
public awareness and improve the understanding of NUT Writing – original draft: Zhuomiao Ye, Xiangwen Luo, Xin
carcinoma among medical professionals. This platform Li, Minghui Zhang
(http://resource.yin-lab.com/NUT/) provides scientific Writing – review & editing: All authors
information about NUT carcinoma and continuously
updates all published cases and available cohort data, Ethics approval and consent to participate
facilitating better research on this rare disease. Furthermore,
it will support the publication of relevant clinical trials on Not applicable.
NUT carcinoma in different countries, making it easier for Consent for publication
patients to access appropriate clinical trials. With growing
awareness and a broader understanding of NUT carcinoma Not applicable.
among clinicians, pathologists, radiologists, and cancer
researchers, we believe that the diagnosis and treatment of Availability of data
NUT carcinoma can improve, ultimately benefiting more The data supporting the findings of this study are available
patients in the future. from the corresponding author on reasonable request.
Acknowledgments Some data may not be made available due to privacy or
ethical restrictions.
We extend our sincere gratitude to all the experts who
contributed to the development of the Expert Consensus References
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members who participated in the retrieval, screening, children and adolescents: The expert European standard
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2. Luo W, Stevens TM, Stafford P, Miettinen M, Gatalica Z,
Funding Vranic S. NUTM1-rearranged neoplasms-a heterogeneous
group of primitive tumors with expanding spectrum of
This work was supported in part by the Chongqing Wanzhou histology and molecular alterations-an updated review. Curr
Municipal Science and Health Joint Medical Research Oncol. 2021;28(6):4485-4503.
Project Key Program (grant no. wzstc-kw2023001), the
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Project (grant no. Wzstc20230402), and the Chongqing 3. Kees UR, Mulcahy MT, Willoughby ML. Intrathoracic
Natural Science Foundation (grant no. CSTB2023NSCQ- carcinoma in an 11-year-old girl showing a translocation
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Kalevi Kairemo, Mohamed Kamal, Evan T. Keller, Mikael World Health Organization classification of lung tumors:
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Volume 3 Issue 4 (2024) 23 doi: 10.36922/td.4904