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Tumor Discovery                                                    EpCAM-targeting cancer immunotherapies



            of Science and Technology administered through the      doi: 10.15698/cst2019.06.188
            National Research Foundation of South Africa (Grant   8.   Lei Z, Liu W, Nie Y, Yang Y, Chen G, Huang L. EpCAM
            Number 47904).                                        is essential to maintaining the immune homeostasis of
                                                                  intestines via keeping the expression of pIgR in the intestinal
            Conflict of interest                                  epithelium of mice. Front Immunol. 2022;13:1-15.
            The authors declare no conflicts of interest.         doi: 10.3389/fimmu.2022.843378

            Author contributions                               9.   Siddiqui H, Rawal P, Bihari C, Arora N, Kaur S. Vascular
                                                                  endothelial growth factor promotes proliferation of epithelial
            Conceptualization: Dennis Makafui Dogbey, Stefan Barth  cell adhesion molecule-positive cells in nonalcoholic
            Writing–original draft:  Dennis  Makafui  Dogbey, Ursula-  steatohepatitis. J Clin Exp Hepatol. 2020;10:275-283.
               Claire Andong-Koung-Edzidzi, Gomolemo Atlegang      doi: 10.1016/j.jceh.2019.11.011
               Molope, Jesmika Singh, Tatenda Lovemore Bvudzijena
            Writing–review & editing: Krupa Naran, Stefan Barth  10.  Schwartzberg LS. Clinical experience with edrecolomab:
                                                                  A  monoclonal  antibody  therapy for  colorectal  carcinoma.
            Ethics approval and consent to participate            Crit Rev Oncol Hematol. 2001;40:17-24.
                                                                  doi: 10.1016/S1040-8428(01)00131-7
            Not applicable.
                                                               11.  Punt CJ, Nagy A, Douillard JY,  et al. Edrecolomab alone
            Consent for publication                               or in combination with fluorouracil and folinic acid in the
                                                                  adjuvant treatment of stage III colon cancer: A randomised
            Not applicable.                                       study. Lancet. 2002;360:671-677.
            Availability of data                                  doi: 10.1016/S0140-6736(02)09836-7

            Not applicable.                                    12.  Oberneder R, Weckermann D, Ebner B, et al. A phase I study
                                                                  with adecatumumab, a human antibody directed against
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            Volume 4 Issue 1 (2025)                         10                                doi: 10.36922/td.4926
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