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Artificial Intelligence in Health





                                        REVIEW ARTICLE
                                        LLMs-Healthcare: Current applications and

                                        challenges of large language models in various
                                        medical specialties



                                        Ummara Mumtaz , Awais Ahmed , and Summaya Mumtaz *
                                                                                           1
                                                                     2
                                                       1
                                        1 Department  of  Information Technology,  University  of  the  Cumberlands, Williamsburg,  Kentucky,
                                        United States of America
                                        2 Department of Gynecology and Obstetrics, University of Concepción, Concepción, Chile



                                        Abstract

                                        The purpose of this review is to provide a comprehensive overview of the latest
                                        advancements in utilizing large language models (LLMs) in the health-care sector,
                                        emphasizing their transformative impact across various medical domains. LLMs
                                        have become pivotal in supporting healthcare, including physicians, health-care
                                        providers, and patients. Our review provides insight into the applications of LLMs in
                                        healthcare, specifically focusing on diagnostic and treatment-related functionalities.
                                        We shed light on how LLMs are applied in cancer care, dermatology, dental care,
                                        neurodegenerative disorders, and mental health, highlighting their innovative
                                        contributions to medical diagnostics and patient care.  Throughout our analysis,
                                        we explore the challenges and opportunities associated with integrating LLMs in
                                        healthcare, recognizing their potential across various medical specialties despite
                                        existing limitations. In addition, we offer an overview of handling diverse data types
            *Corresponding author:
            Summaya Mumtaz              within the medical field.
            (summaya.mumtaz@gmail.com)
            Citation: Mumtaz U, Ahmed A,   Keywords: Large language models; Medical specialties; Cancer; Mental health;
            Mumtaz S. LLMs-Healthcare:   Healthcare; Diagnosis and treatments; Clinical notes; Dermatology
            Current applications and challenges
            of large language models in various
            medical specialties. Artif Intell
            Health. 2024;1(2): 16-28.
            doi: 10.36922/aih.2558      1. Introduction
            Received: December 28, 2023
                                        The field of artificial intelligence (AI) has undergone a remarkable evolution in recent
            Accepted: February 23, 2024  years, with significant advancements, particularly noticeable in natural language
            Published Online: April 2, 2024  processing (NLP) and the development of large language models (LLMs). These models
                                        represent a paradigm shift in AI’s capability to understand, generate, and interact using
            Copyright: © 2024 Author(s).
            This is an Open-Access article   human language. At their foundation, LLMs are complex algorithms trained on vast,
                                                                    1
            distributed under the terms of the   text-based documents and datasets.  Such extensive training allows them to recognize
            Creative Commons Attribution   patterns adeptly, predict subsequent words in a sentence, and generate coherent,
            License, permitting distribution,
            and reproduction in any medium,   contextually relevant text for the specified inputs, often called prompts within the NLP
            provided the original work is   community. This ability demonstrates the technical prowess of LLMs and signifies their
            properly cited.             potential to revolutionize how machines understand and process human language.
            Publisher’s Note: AccScience   One of the most prominent features of LLMs is their proficiency in processing and
            Publishing remains neutral with   analyzing large volumes of text rapidly and accurately, a capability that far surpasses
            regard to jurisdictional claims in                           2
            published maps and institutional   human potential in speed and efficiency.  This quality makes them indispensable in
            affiliations.               areas requiring the analysis of extensive data sets. They are also known as “few-shot”

            Volume 1 Issue 2 (2024)                         16                               doi: 10.36922/aih.2558
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