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Artificial Intelligence in Health                            AI in medical diagnostics: A multi-disease approach



              AI is also being deployed in developing nations, where   were hesitant about data sharing for AI development. The
            healthcare resources are limited. With the increasing   scarcity of real, accessible patient data limits the potential
            availability of computers and internet access, AI-driven   of AI in healthcare, with fears exacerbated by the lack of
            diagnostic tools are providing life-saving services to people   regulations governing AI usage in countries like the U.S.
            in areas with limited access to healthcare professionals.   Concerns about data being misused for financial gain,
            This helps to reduce outsourcing and improve the quality   as exemplified by Roche’s purchase of healthcare data for 2
            of care. AI systems in these regions are tailored to offer   million cancer patients, question whether patient data can
            individualized treatments, adjusting based on real-time   or should have a monetary value, raising broader ethical
            data, thus improving patient outcomes in resource-  debates around fairness and patient consent. Automation
            constrained settings.                              in healthcare also stirs controversy. While AI has yet to
              However, the widespread adoption of AI in healthcare   replace healthcare jobs, research shows that automation
            brings with it several regulatory and ethical concerns.   might affect roles that handle digital information, such as
            The  risks  associated with AI,  such  as algorithmic  bias,   radiology and pathology. A 2019 study in the UK estimated
            patient  data  privacy,  and  the  implications  of  machine   that AI could replace up to 35% of jobs within two decades,
            morality, necessitate stringent regulations. There are   though doctor-patient interactions are less likely to be
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            established reporting guidelines, such as TRIPOD-AI,   impacted.  On the positive side, AI offers the potential to
            DECIDE-AI, and CONSORT-AI, that ensure AI studies   enhance healthcare by alleviating burnout and cognitive
            are transparently reported for regulatory approval. In the   overload for medical professionals, allowing them to
            U.S., HIPAA safeguards patient data, while GDPR protects   focus more on patient care. AI is even being applied in
            patient data in the European Union.                elder care, where robots assist with entertainment and
                                                               companionship, allowing caregivers to provide more one-
              The U.S. FDA has developed a plan to regulate    on-one care. Despite these benefits, skepticism remains
            AI-based medical devices, focusing on areas such as good   about whether AI can offer the empathy provided by
            ML practices and algorithm bias. Ethical concerns in AI   human healthcare professionals, as found in a 2023
            include the balance between patient autonomy and the   thematic review. 55,61,68  Bias in AI systems is another critical
            use of AI in making critical healthcare decisions. The U.S.   concern. AI’s reliance on input data means that if the data
            Department  of  Health  and  Human  Services  has  issued   are biased or unrepresentative, it can lead to discriminatory
            guidelines emphasizing the ethical principles of autonomy,   outcomes.
            beneficence, non-maleficence, and justice. Similarly, the
            GDPR in Europe protects citizens’ data, ensuring fairness,   Medical AI systems can unintentionally perpetuate
            transparency, and respect for human dignity in AI-driven   social and healthcare inequities by making more accurate
            processes. As AI continues to shape healthcare, balancing   predictions for majority populations, such as White males,
            innovation with patient rights and ethical standards will   who are overrepresented in medical datasets.  This can
            remain a key challenge for regulators globally.    result in worse outcomes for minorities. Collecting data
                                                               from minority communities, while essential for balanced
              Finally, international efforts to standardize AI   algorithms, can also lead to medical discrimination,
            use in healthcare are underway. The joint World    such as the potential misuse of data related to conditions
            Health Organization (WHO) and the International    like acquired immunodeficiency syndrome. Beyond
            Telecommunication Union (ITU) (ITU-WHO) Focus      demographic biases, differences in clinical systems and
            Group on AI for Health (FG-AI H) has been benchmarking   work practices also introduce variability in AI functionality.
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            AI applications in medical settings, including cancer   However, many of these biases can be mitigated through
            risk assessment and diagnosis from medical imagery.   careful  data  collection  and  algorithm  design.  A  specific
            These initiatives reflect the growing importance of   form of bias, “label choice bias,” arises when proxy measures
            ensuring that AI in healthcare is safe, effective, and   are used in algorithms, such as using healthcare costs to
            ethical, while promoting innovations that improve global   predict patient needs, which can skew results against
            health outcomes. 7-75  The use of AI in healthcare presents   certain groups, like Black  patients. 68,76  Addressing these
            significant ethical concerns, especially regarding data   biases requires closer alignment between the target of the
            collection, automation, and bias. One of the key issues is the   AI prediction and the actual healthcare needs of patients.
            massive amount of data required to train AI systems, often   Historically, AI in healthcare has evolved since the 1960s
            sourced from patients. This raises privacy concerns, as   and 1970s, starting with expert systems such as Dendral
            many individuals are uncomfortable with sharing personal   and MYCIN, which laid the groundwork for future AI
            health information for technological advancements.   applications in medicine. 15-75  Although these early systems
            A  survey in the UK  revealed that 63% of  respondents   did not achieve widespread clinical use, they highlighted


            Volume 2 Issue 3 (2025)                         49                               doi: 10.36922/aih.5173
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