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Artificial Intelligence in Health                            AI in medical diagnostics: A multi-disease approach



            of  receiver  operating  characteristic  (ROC)  curves.   diagnostic accuracy across demographic groups, including
            Classification accuracy measured the proportion of correct   age, gender, and ethnicity. Bias mitigation techniques, such
            predictions, while sensitivity quantified the ability to detect   as fairness-aware algorithms and regularization methods,
            true positive cases.                               were applied to reduce disparities. Ethical considerations
              Specificity assessed the accuracy in identifying true   included patient data privacy, the implications of AI-driven
            negative cases, and precision captured the proportion   diagnostic errors, and the need for regulatory frameworks
                                                               that support AI integration into healthcare while protecting
            of true positives relative to all positive predictions. The   patient welfare. These measures ensure the responsible
            F1-score offered a very balanced metric that combines   deployment of AI within the sensitive domain of medical
            both precision and recall, making it particularly useful   diagnostics, emphasizing the importance of accuracy,
            for evaluating performance on the various types of   equity, and transparency.
            imbalanced datasets. The AUC-ROC provided an overall
            assessment of model performance across different   3. Background research on available
            classification thresholds. These results were benchmarked   knowledge
            against traditional diagnostic methods to gauge potential
            improvements in diagnostic accuracy, efficiency, and speed   AI in healthcare represents a significant technological
            across the four disease categories.                advancement, simulating human cognition to analyze,
                                                               interpret,  and present complex medical  and healthcare
              The experiments were conducted using high-       data. This ability not only mimics human thought processes
            performance computing infrastructure capable of    but also enhances healthcare delivery by enabling faster
            managing extensive medical datasets and complex model   and more accurate diagnoses, treatments, and preventive
            architectures. The  process involved  three  main phases.   measures.  ML and DL algorithms, key components of
            First,  data  preprocessing  included  image  normalization,   AI, can process vast amounts of clinical data, such as
            augmentation, and management of missing or incomplete   EHRs, to support physicians in making quicker and
            clinical data to improve model training reliability. During   more precise diagnoses. By analyzing large datasets, AI
            the training and validation phase, 80% of the dataset was   can  aid  in  disease  prediction  and  treatment,  helping
            allocated for training, with the remaining 20% reserved for   clinicians save time and improve patient outcomes.  AI
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            validation. Model fine-tuning employed backpropagation   is instrumental in bringing culturally competent practices
            with the Adam optimizer and cross-entropy loss functions   to the healthcare industry, ensuring more tailored and
            to optimize the performance of the model. Finally, model   inclusive patient care. AI’s applications in healthcare span
            testing was carried out on unseen data from diverse   numerous areas, including diagnostics, treatment protocol
            patient cohorts to assess generalizability. Predictions were   development, drug discovery, personalized medicine, and
            validated against expert-reviewed ground truth labels   patient monitoring. In radiology, AI’s role is particularly
            and clinical diagnoses, ensuring alignment  with clinical   noteworthy for interpreting and triaging X-ray images,
            standards. A detailed comparative analysis was performed   one of the most commonly used imaging tests.  AI can
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            to assess the AI models across disease categories, focusing   analyze these images, helping radiologists prioritize
            on the models’ diagnostic efficacy within specific disease   critical cases and reducing wait times. However, despite
            contexts. In cancer diagnostics, models were evaluated for   its  promising  potential,  the  widespread  adoption  of  AI
            the early-stage detection and tumor segmentation accuracy,   in healthcare faces challenges, including ethical concerns
            while in cardiovascular diseases, the focus was on detecting   about data privacy, job automation, and the amplification
            arrhythmias, coronary artery disease, and heart failure. For   of biases. Moreover, resistance from healthcare leaders to
            neurological disorders, early detection of Alzheimer’s and   embrace new AI technologies has slowed its integration
            Parkinson’s diseases from magnetic resonance imaging   into mainstream medical practices.
            (MRI) data was emphasized. For infectious diseases, the   In terms of disease diagnosis, AI plays a pivotal role
            models’ ability to analyze chest X-rays for the detection of   by helping clinicians navigate complex medical data to
            coronavirus disease 2019 (COVID-19) and tuberculosis   identify conditions accurately. By leveraging vast EHR
            was examined. This cross-disease comparison highlighted   datasets, AI algorithms can predict diseases such as
            the strengths and limitations of AI models within each   Alzheimer’s and dementia, providing early diagnosis and
            diagnostic scenario, allowing for an understanding of AI’s   potentially improving treatment outcomes.  In emergency
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            capabilities and challenges in a clinical setting.
                                                               settings, AI can prioritize urgent cases by providing real-
              To address fairness and ethical concerns, the study   time data interpretation to assist decision-making, thereby
            incorporated bias detection and mitigation strategies.   enhancing efficiency and potentially saving lives. Studies
            Subgroup analyses were conducted to examine variations in   have shown that AI, through platforms like ChatGPT, can


            Volume 2 Issue 3 (2025)                         46                               doi: 10.36922/aih.5173
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