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Advanced Neurology                                                        TRPM2 in neurological disorders



               neurofibrillary degeneration in transgenic mice expressing   models of ischemic stroke and their application in clinical
               mutant tau and APP. Science, 293(5534): 1487–1491.   research. Drug Des Devel Ther, 9: 3445–3454.
               https://doi.org/10.1126/science.1058189            https://doi.org/10.2147/DDDT.S56071
            57.  Kitazawa M, Medeiros R, Laferla FM, 2012, Transgenic   68.  Orset C, Macrez R, Young AR, et al., 2007, Mouse model
               mouse  models  of  alzheimer  disease:  Developing  a  better   of in situ thromboembolic stroke and reperfusion. Stroke,
               model as a tool for therapeutic interventions. Curr Pharm   38(10): 2771–2778.
               Des, 18(8): 1131–1147.
                                                                  https://doi.org/10.1161/STROKEAHA.107.487520
               https://doi.org/10.2174/138161212799315786
                                                               69.  Li H, Yang Z, Tang Q, et al., 2021, Embolic stroke model
            58.  Li X, Jiang LH, 2018, Multiple molecular mechanisms form   with magnetic nanoparticles.  ACS Appl Mater Interfaces,
               a positive feedback loop driving amyloid  β42 peptide-  13(37): 43993–44001.
               induced neurotoxicity via activation of the TRPM2 channel      https://doi.org/10.1021/acsami.1c11377
               in hippocampal neurons. Cell Death Dis, 9(2): 195.
                                                               70.  Uzdensky AB, 2018, Photothrombotic stroke as a model of
               https://doi.org/10.1038/s41419-018-0270-1
                                                                  ischemic stroke. Transl Stroke Res, 9(5): 437–451.
            59.  Fonfria E, Marshall IC, Boyfield I,  et  al., 2005, Amyloid      https://doi.org/10.1007/s12975-017-0593-8
               beta-peptide(1-42) and hydrogen peroxide-induced toxicity
               are mediated by TRPM2 in rat primary striatal cultures.   71.  Traystman RJ, 2003, Animal models of focal and global
               J Neurochem, 95(3): 715–723.                       cerebral ischemia. ILAR J, 44(2): 85–95.
               https://doi.org/10.1111/j.1471-4159.2005.03396.x     https://doi.org/10.1093/ilar.44.2.85
            60.  Li F, Abuarab N, Sivaprasadarao A, 2017, TRPM2: Shredding   72.  Smith ML, Bendek G, Dahlgren N, et al., 1984, Models for
               the mitochondrial network. Channels (Austin), 11(6): 507–509.  studying long-term recovery following forebrain ischemia
                                                                  in the rat. 2. A 2-vessel occlusion model. Acta Neurol Scand,
               https://doi.org/10.1080/19336950.2017.1376982
                                                                  69(6): 385–401.
            61.  Ostapchenko VG, Chen M, Guzman MS, et al., 2015, The      https://doi.org/10.1111/j.1600-0404.1984.tb07822.x
               transient receptor potential melastatin 2 (TRPM2) channel
               contributes to  β-amyloid oligomer-related neurotoxicity   73.  Bacigaluppi  M,  Comi  G,  Hermann  DM,  2010,  Animal
               and memory impairment. J Neurosci, 35(45): 15157–15169.  models of ischemic stroke. Part two: Modeling cerebral
                                                                  ischemia. Open Neurol J, 4: 34–38.
               https://doi.org/10.1523/JNEUROSCI.4081-14.2015
                                                                  https://doi.org/10.2174/1874205X01004020034
            62.  Mortadza SA, Sim JA, Neubrand VE, et al., 2018, A critical
               role of TRPM2 channel in Aβ42-induced microglial   74.  Fonfria E, Mattei C, Hill K, et al., 2006, TRPM2 is elevated
               activation and generation of tumor necrosis factor-α. Glia,   in  the tMCAO  stroke model, transcriptionally regulated,
               66(3): 562–575.                                    and functionally expressed in C13 microglia. J Recept Signal
                                                                  Transduct Res, 26(3): 179–198.
               https://doi.org/10.1002/glia.23265
                                                                  https://doi.org/10.1080/10799890600637522
            63.  Kakae M, Miyanohara J, Morishima M,  et  al., 2019,
               Pathophysiological role of TRPM2 in age-related cognitive   75.  Alim I, Teves L, Li R, et al., 2013, Modulation of NMDAR
               impairment in mice. Neuroscience, 408: 204–213.    subunit expression by TRPM2 channels regulates neuronal
                                                                  vulnerability  to  ischemic  cell  death.  J  Neurosci,  33(44):
               https://doi.org/10.1016/j.neuroscience.2019.04.012
                                                                  17264–17277.
            64.  Jiang  LH,  Li  X,  Mortadza  SA,  et al.,  2018,  The  TRPM2      https://doi.org/10.1523/JNEUROSCI.1729-13.2013
               channel nexus from oxidative damage to Alzheimer’s
               pathologies: An emerging novel intervention target for age-  76.  Toda T, Yamamoto S, Umehara N, et al., 2019, Protective
               related dementia. Ageing Res Rev, 47: 67–79.       effects of duloxetine against cerebral ischemia-reperfusion
                                                                  injury via transient receptor potential melastatin 2
               https://doi.org/10.1016/j.arr.2018.07.002
                                                                  inhibition. J Pharmacol Exp Ther, 368(2): 246–254.
            65.  Chugh C, 2019, Acute ischemic stroke: Management      https://doi.org/10.1124/jpet.118.253922
               approach. Indian J Crit Care Med, 23(Suppl 2): S140–S146
                                                               77.  Gelderblom M, Melzer N, Schattling B, et al., 2014, Transient
               https://doi.org/10.5005/jp-journals-10071-23192
                                                                  receptor potential melastatin subfamily member 2 cation
            66.  McBride DW, Zhang JH, 2017, Precision stroke animal   channel regulates detrimental immune cell invasion in
               models: The permanent mcao model should be the primary   ischemic stroke. Stroke, 45(11): 3395–3402.
               model, not transient MCAO. Transl Stroke Res, 10: 554.
                                                                  https://doi.org/10.1161/STROKEAHA.114.005836
               https://doi.org/10.1007/s12975-017-0554-2
                                                               78.  Wang GJ, Deng HY, Maier CM, et al., 2002, Mild hypothermia
            67.  Fluri F, Schuhmann MK, Kleinschnitz C, 2015, Animal   reduces ICAM-1 expression, neutrophil infiltration and

            Volume 1 Issue 1 (2022)                         15                        https://doi.org/10.36922/an.v1i1.3
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