Page 95 - AN-1-1

Advanced Neurology TRPM2 in neurological disorders

of a susceptibility locus for bipolar and genetically related https://doi.org/10.1038/s41380-019-0415-3
unipolar affective disorders, to a region containing the 133. Krishnan V, Nestler EJ, 2011, Animal models of depression:
C21ORF29 and TRPM2 genes on chromosome 21q22.3. Molecular perspectives. Curr Top Behav Neurosci, 7: 121–147.
Mol Psychiatry, 11(2): 134–142.
https://doi.org/10.1007/7854_2010_108
https://doi.org/10.1038/sj.mp.4001759
134. Das R, Emon PZ, Shahriar M, et al., 2021, Higher levels of serum
122. Xu C, Li PP, Cooke RG, et al., 2009, TRPM2 Variants and IL-1β and TNF-α are associated with an increased probability
bipolar disorder risk: Confirmation in a family-based of major depressive disorder. Psychiatry Res, 295: 113568.
association study. Bipolar Disord, 11(1): 1–10.
https://doi.org/10.1016/j.psychres.2020.113568
https://doi.org/10.1111/j.1399-5618.2008.00655.x
135. Köhler O, Benros ME, Nordentoft M, et al., 2014, Effect
123. Xu C, Warsh JJ, Wang KS, et al., 2013, Association of the of anti-inflammatory treatment on depression, depressive
iPLA2β gene with bipolar disorder and assessment of its symptoms, and adverse effects: A systematic review
interaction with TRPM2 gene polymorphisms. Psychiatr and meta-analysis of randomized clinical trials. JAMA
Genet, 23(2): 86–89. Psychiatry, 71(12): 1381–1391.
https://doi.org/10.1097/YPG.0b013e32835d700d https://doi.org/10.1001/jamapsychiatry.2014.1611
124. Depression. Available from: https://www.who.int/news- 136. Colaianna M, Schiavone S, Zotti M, et al., 2013,
room/fact-sheets/detail/depression [Last accessed on 2021 Neuroendocrine profile in a rat model of psychosocial
Dec 16]. stress: Relation to oxidative stress. Antioxid Redox Signal,
125. DSM-5. Available from: https://www.psychiatry.org/ 18(12): 1385–1399.
psychiatrists/practice/dsm [Last accessed on 2021 Dec 16]. https://doi.org/10.1089/ars.2012.4569
126. Post RM, Denicoff KD, Leverich GS, et al., 2003, Morbidity 137. Schiavone S, Sorce S, Dubois-Dauphin M, et al., 2009,
in 258 bipolar outpatients followed for 1 year with daily Involvement of NOX2 in the Development of Behavioral
prospective ratings on the NIMH life chart method. J Clin and Pathologic Alterations in Isolated Rats. Biol Psychiatry,
Psychiatry, 64(6): 680–690; quiz 738–739. 66(4): 384–392.
https://doi.org/10.4088/jcp.v64n0610 https://doi.org/10.1016/j.biopsych.2009.04.033
127. Lee S, Jeong J, Kwak Y, et al., 2010, Depression research: 138. Luo X, Li M, Zhan K, et al., 2018, Selective inhibition of
Where are we now? Mol Brain, 3: 8. TRPM2 channel by two novel synthesized ADPR analogues.
Chem Biol Drug Des, 91(2): 552–566.
https://doi.org/10.1186/1756-6606-3-8
https://doi.org/10.1111/cbdd.13119
128. Morilak DA, Frazer A, 2004, Antidepressants and brain
monoaminergic systems: A dimensional approach to 139. Hu HZ, Gu Q, Wang C, et al., 2004, 2-aminoethoxydiphenyl
understanding their behavioural effects in depression and Borate is a Common Activator of TRPV1, TRPV2, and
anxiety disorders. Int J Neuropsychopharmacol, 7(2): 193–218. TRPV3. J Biol Chem, 279(34): 35741–35748.
https://doi.org/10.1017/S1461145704004080 https://doi.org/10.1074/jbc.M404164200
129. Juszczyk G, Mikulska J, Kasperek K, et al., 2021, Chronic 140. Qi Z, Shi W, Zhao Y, et al., 2019, Zinc accumulation in
stress and oxidative stress as common factors of the mitochondria promotes ischemia-induced BBB disruption
pathogenesis of depression and Alzheimer’s disease: The role through Drp1-dependent mitochondria fission. Toxicol Appl
of antioxidants in prevention and treatment. Antioxidants Pharmacol, 377: 114601.
(Basel), 10(9): L1439. https://doi.org/10.1016/j.taap.2019.114601
https://doi.org/10.3390/antiox10091439 141. Manna PT, Munsey TS, Abuarab N, et al., 2015, TRPM2-
2+
130. Maeng SH, Hong H, 2019, Inflammation as the potential mediated intracellular Zn release triggers pancreatic β-cell
basis in depression. Int Neurourol J, 23(Suppl 2): S63–S71. death. Biochem J, 466(3): 537–546.
https://doi.org/10.5213/inj.1938226.113 https://doi.org/10.1042/BJ20140747
131. Willner P, 2017, The chronic mild stress (CMS) model of 142. Feng Y, Wang X, 2012, Antioxidant therapies for Alzheimer’s
depression: History, evaluation and usage. Neurobiol Stress, disease. Oxid Med Cell Longev, 2012: 472932.
6: 78–93. https://doi.org/10.1155/2012/472932
https://doi.org/10.1016/j.ynstr.2016.08.002 143. Naziroğlu M, Lückhoff A, 2008, Effects of antioxidants on
calcium influx through TRPM2 channels in transfected cells
132. Fox ME, Lobo MK, 2019, The molecular and cellular
mechanisms of depression: A focus on reward circuitry. Mol activated by hydrogen peroxide. J Neurol Sci, 270(1-2): 152–158.
Psychiatry, 24(12): 1798–1815. https://doi.org/10.1016/j.jns.2008.03.003

Volume 1 Issue 1 (2022) 18 https://doi.org/10.36922/an.v1i1.3