Page 71 - AN-1-2
P. 71
Advanced Neurology NMDA receptors in neuropsychiatric diseases
Province (BE2019707), Special Fund for Science and 9. Panza, F, Solfrizzi V, Seripa D, et al., 2015, Progresses in
Technology Innovation Strategy of Guangdong Province treating agitation: A major clinical challenge in Alzheimer’s
(2021B0909050004), and the Fundamental Research disease. Expert Opin Pharmacother, 16: 2581–2588.
Funds for the Central Universities (021414380524). https://doi.org/10.1517/14656566.2015.1092520
Conflict of interest 10. Song J, Patel RV, Sharif M, et al., 2022, Chemogenetics as
a neuromodulatory approach to treating neuropsychiatric
The authors declare no competing interests. diseases and disorders. Mole Ther, 30: 990–1005.
Author contributions https://doi.org/10.1016/j.ymthe.2021.11.019
Conceptualization: Yun Stone Shi, Qing-Qing Li 11. Thompson PM, Andreassen OA, Arias-Vasquez A, et al.,
2017, ENIGMA and the individual: Predicting factors that
Writing – original draft: Qing-Qing Li, Xiao Lin affect the brain in 35 countries worldwide. NeuroImage,
Writing – review and editing: Yun Stone Shi. 145(Pt B): 389–408.
https://doi.org/10.1016/j.neuroimage.2015.11.057
References
12. Schang AL, Saberan-Djoneidi D, Mezger V, 2018, The impact
1. Traynelis SF, Wollmuth LP, McBain CJ, et al., 2010, of epigenomic next-generation sequencing approaches
Glutamate receptor ion channels: Structure, regulation, and on our understanding of neuropsychiatric disorders. Clin
function. Pharmacol Rev, 62(3): 405–496. Genet, 93(3): 467–480.
https://doi.org/10.1124/pr.109.002451 https://doi.org/10.1111/cge.13097
2. Alzheimer’s Association, 2022, 2022 Alzheimer’s disease 13. Dorado G, Galvez S, Rosales TE, et al., 2021, Analyzing
facts and figures. Alzheimers Dement, 18(4): 700–789. modern biomolecules: The revolution of nucleic-acid
https://doi.org/10.1002/alz.12638 sequencing review. Biomolecules, 11(8): 1111.
3. Avila J, Perry GA, 2021, Multilevel view of the development https://doi.org/10.3390/biom11081111
of Alzheimer’s disease. Neuroscience, 457: 283–293. 14. Dehghan A, 2018, Genome-wide association studies.
https://doi.org/10.1016/j.neuroscience.2020.11.015 Methods Mol Biol, 1793: 37–49.
4. Christensen DL, Baio J, Braun KV, et al., 2018, Prevalence https://doi.org/10.1007/978-1-4939-7868-7_4
and characteristics of autism spectrum disorder among 15. Qin Y, Du Y, Chen L, et al., 2022, A recurrent SHANK1
children aged 8 year autism and developmental disabilities mutation implicated in autism spectrum disorder causes
monitoring network, 11 sites, United States, 2012. Morb autistic-like core behaviors in mice via downregulation of
Mort Wkly Rep, 65: 1–23.
mGluR1-IP3R1-calcium signaling. Mole Psychiatry, 27(7):
https://doi.org/10.15585/mmwr.ss6513a1 2985–2998.
5. Lord C, Brugha TS, Charman T, et al., 2020, Autism https://doi.org/10.1038/s41380-022-01539-1
spectrum disorder. Nat Rev Dis Primers, 6(1): 5.
16. Peng SX, Pei J, Ge Y, et al., 2022, Dysfunction of AMPA
https://doi.org/10.1038/s41572-019-0138-4 receptor GluA3 is associated with aggressive behavior in
6. Anderson RM, Hadjichrysanthou C, Evans S, et al., 2017, human. Mol Psychiatry, Online ahead of print.
Why do so many clinical trials of therapies for Alzheimer’s https://doi.org/10.1038/s41380-022-01659-8
disease fail? Lancet, 390: 2327–2329.
17. Li QQ, Chen J, Hu P, et al., 2022, Enhancing GluN2A-
https://doi.org/10.1016/S0140-6736(17)32399-1 type NMDA receptors impairs long-term synaptic plasticity and
7. Mitsumoto H, Brooks BR, Silani V, 2014, Clinical trials learning and memory. Mol Psychiatry, Online ahead of print.
in amyotrophic lateral sclerosis: Why so many negative https://doi.org/10.1038/s41380-022-01579-7
trials and how can trials be improved? Lancet Neurol,
13: 1127–1138. 18. Teng XY, Hu P, Chen Y, et al., 2022, A novel Lgi1 mutation
causes white matter abnormalities and impairs motor
https://doi.org/10.1016/S1474-4422(14)70129-2 coordination in mice. FASEB J, 36: e22212.
8. Henriquez F, Cabello V, Baez S, et al., 2021, Multidimensional https://doi.org/10.1096/fj.202101652R
clinical assessment in frontotemporal dementia and its
spectrum in latin America and the Caribbean: A narrative 19. Hall J, Bray NJ, 2022, Schizophrenia genomics: Convergence
review and a glance at future challenges. Front Neurol, on synaptic development, adult synaptic plasticity, or both?
12: 768591. Biol Psychiatry, 91(8): 709–717.
https://doi.org/10.3389/fneur.2021.768591 https://doi.org/10.1016/j.biopsych.2021.10.018
Volume 1 Issue 2 (2022) 15 https://doi.org/10.36922/an.v1i2.148

