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Advanced Neurology                                          A novel approach to mitigate muscle atrophy in GBS



            M-gammaglobinemia, and skin changes [POEMS]). The     268: 2402–2419.
            current research in omega-3 supplementation in relation      https://doi.org//10.1007/s00415-020-09742-2
            to nerve and muscle health has shown intriguing promise;
            however, future investigations must explore this potential   3.   Pithadia AB, Kakadia N, (2010), Guillain-Barré syndrome
            lest it remain theoretical.                           (GBS). Pharmacol Rep, 62: 220–232.
                                                                  https://doi.org//10.1016/s1734-1140(10)70261-9
            Acknowledgments
                                                               4.   Mirian A, Nicolle MW, Budhram A, (2021), Guillain-Barré
            We would like to thank Chris McGlory for his contribution   syndrome. Can Med Assoc J, 193: E378–E378.
            in the direction of this paper.                       https://doi.org//10.1503/cmaj.202710
            Funding                                            5.   Florian IA, Lupan I, Sur L, et al., (2021), To be, or not to be…
                                                                  Guillain-Barré syndrome. Autoimmun Rev, 20: 102983.
            None.
                                                                  https://doi.org//10.1016/j.autrev.2021.102983
            Conflict of interest                               6.   Fokke C, van den Berg B, Drenthen J, et al., (2014), Diagnosis

            All authors deny any conflicts or competing interests   of Guillain-Barré syndrome and validation of Brighton
            with any institutes, organizations or agencies that might   criteria. Brain, 137: 33–43.
            influence the integrity of results or objective interpretation      https://doi.org//10.1093/BRAIN/AWT285
            of this submission.                                7.   van den Berg B, Walgaard C, Drenthen J,  et al., (2014),

            Author contributions                                  Guillain-Barré  syndrome:  Pathogenesis,  diagnosis,
                                                                  treatment and prognosis. Nat Rev Neurol, 10: 469–482.
            Conceptualization: Kevin Cheung, Matti D. Allen       https://doi.org/10.1038/nrneurol.2014.121
            Visualization: Kevin Cheung
            Writing – original draft: Kevin Cheung             8.   Querol L, Lleixà C, (2021), Novel immunological and
            Writing – review & editing: Sussan Askari, Matti D. Allen  therapeutic insights in Guillain-Barré syndrome and CIDP.
                                                                  Neurotherapeutics, 18: 2222–2235.
            Ethics approval and consent to participate            https://doi.org/10.1007/s13311-021-01117-3
            Not applicable.                                    9.   Rajabally YA, Uncini A, (2012), Outcome and its predictors
                                                                  in Guillaine-Barré syndrome. J Neurol Neurosurg Psychiatry,
            Consent for publication                               83: 711–718.
            Not applicable.                                       https://doi.org/10.1136/jnnp-2011-301882

            Availability of data                               10.  Harbo T, Markvardsen LK, Hellfritzsch MB, et al., (2019),
                                                                  Neuromuscular electrical stimulation in early rehabilitation
            Not applicable.                                       of Guillain-Barré syndrome: A  pilot study.  Muscle Nerve,
                                                                  59: 481–484.
            Further disclosure
                                                                  https://doi.org/10.1002/MUS.26396
            A single essay version of this article was previously   11.  Albers JW, Donofrio PD, McGonagle TK, (1985), Sequential
            submitted to the 2022 Canadian Association of Physical   electrodiagnostic abnormalities  in acute inflammatory
            Medicine & Rehabilitation Medical Student Essay Contest   demyelinating  polyradiculoneuropathy.  Muscle Nerve,
            on April 1, 2022. There would be approximately 70%    8: 528–539.
            overlap in content with this published article. The scope
            of the essay would have been identical to this article. To      https://doi.org/10.1002/MUS.880080609
            the best of the author’s knowledge, this essay has remained   12.  Van Den Berg B, Storm EF, Garssen MJ, et al., (2018), Clinical
            unpublished.                                          outcome of Guillain-Barré syndrome after prolonged
                                                                  mechanical ventilation.  J  Neurol Neurosurg Psychiatry,
            References                                            89: 949–954.
            1.   Willison HJ, Jacobs BC, van Doorn PA, (2016), Guillain-     https://doi.org/10.1136/JNNP-2018-317968
               Barré syndrome. Lancet, 388: 717–727.           13.  Ferguson EJ, Seigel JW, McGlory C, (2021), Omega-3 fatty
               https://doi.org//10.1016/S0140-6736(16)00339-1     acids and human skeletal muscle.  Curr Opin Clin Nutr
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            Volume 2 Issue 2 (2023)                         8                          https://doi.org/10.36922/an.280
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