Page 43 - AN-2-4
P. 43

Advanced Neurology                                         Evoked potential response in parkinsonian syndromes



            axonal variety in the visual, auditory, and somatosensory   Availability of data
            pathways. Despite being predominantly motor disorders,
            these  diseases  are  also  tied  with  profound  non-  Data used in this work are available from the corresponding
            motor components, necessitating assessments of the   author upon reasonable request.
            electrophysiological abnormalities, which have been found   References
            to correlate with disease severity and disease duration. The
            visual pathways, from the anterior visual pathways to the   1.   Jankovic J, Mcdermott M, Carter J,  et al., 1990, Variable
                                                                  expression of Parkinson’s disease: A base-line analysis of the
            higher visual processing centers, are heavily impacted in   DATATOP cohort, The Parkinson study group, Neurology,
            IPD and APS.
                                                                  40: 1529–1534.
              The evoked potential tests are able to detect the relevant      https://doi.org/10.1212/wnl.40.10.1529
            abnormalities, especially in the early stages of the disease
            while the brain MRI fails to pick up any abnormal findings.   2.   Marsden CD, 1990, Parkinson’s disease, Lancet, 335: 948–952.
            Contrary to the popular belief that only nigrostriatal      https://doi.org/10.1016/0140-6736(90)91006-v
            dopaminergic pathway is involved, IPD is characterized   3.   Jankovic J, 1989, Parkinsonism plus syndromes, Mov Disord,
            by  a  widespread  brain  involvement.  PIGD  and  tremor-  4: 95119.
            dominant  IPD patients  are significantly  different  in      https://doi.org/10.1002/mds.870040512
            terms  of  BAER  findings,  denoting  a  significantly  higher
            brainstem involvement in the PIGD variant.         4.   Gawel MJ, Das P, Vincent S, et al., 19881, Visual and auditory
                                                                  evoked responses in patients with Parkinson’s disease,  J
            Acknowledgments                                       Neurol Neurosurg Psychiatry 44: 227–232.
            None.                                                 https://doi.org/10.1136/jnnp.44.3.227
                                                               5.   Gelb DJ, Oliver E, Gilman S, 1999, Diagnostic criteria for
            Funding                                               Parkinson’s disease, Arch Neurol, 56: 33–39.
            None.                                                 https://doi.org/10.1001/archneur.56.1.33
            Conflict of interest                               6.   Williams DR, Lees AJ, 2009, Progressive supranuclear palsy:
                                                                  Clinicopathological concepts and diagnostic challenges,
            The authors declare that they have no competing interests.  Lancet Neurol, 8: 270–279.

            Author contributions                                  https://doi.org/10.1016/S1474-4422(09)70042-0
                                                               7.   Gilman S, Wenning GK, Low PA,  et al., 2008, Second
            Conceptualization: Manoj Roy, Amar Kumar Misra,       consensus  statement  on  the  diagnosis  of  multiple  system
            Formal analysis: Joydeep Mukherjee, Jasodhara Chaudhuri  atrophy, Neurology, 71: 670–676.
            Investigation: Manoj Roy, Manamita Mandal, Bijendra      https://doi.org/10.1212/01.wnl.0000324625.00404.15
               Mohanty
            Methodology:  Manoj Roy, Amar  Kumar  Misra,  Joydeep   8.   Kertesz A, Blair M, McMonagle P, et al., 2007, The diagnosis
               Mukherjee                                          and course of frontotemporal dementia, Alzheimer Dis Assoc
            Writing – original draft: Manoj Roy, Joydeep Mukherjee  Disord, 21: 155–163.
            Writing – review & editing: Amar Kumar Misra, Joydeep      https://doi.org/10.1097/WAD.0b013e31806547eb
               Mukherjee, Kartik Chandra Ghosh                 9.   McKeith IG, Galasko D, Kosaka K, et al., 1996, Consensus
                                                                  guidelines for the clinical and pathologic diagnosis of
            Ethics approval and consent to participate            dementia with Lewy bodies (DLB): Report of the consortium
            This study was approved by the NRS Medical College    on DLB international workshop, Neurology, 47: 1113–1124.
            Institutional Ethics Committee (NMC/958).             https://doi.org/10.1212/wnl.47.5.1113
              Informed consent was taken from all participants   10.  Liu C, Zhang Y, Tang W,  et al., 2017, Evoked potential
            before enrolment.                                     changes in patients with Parkinson’s disease, Brain Behav, 7:
                                                                  e00703.
            Consent for publication                               https://doi.org/10.1002/brb3.703
            We obtained informed consent of the study subjects for   11.  Inzelberg R, Ramirez JA, Nisipeanu P, et al., 2004, Retinal
            publishing  their  data  without  revealing  their  identity  in   nerve fiber layer thinning in Parkinson disease, Vision Res,
            scientific research articles.                         44: 279.



            Volume 2 Issue 4 (2023)                         12                        https://doi.org/10.36922/an.1907
   38   39   40   41   42   43   44   45   46   47   48