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Advanced Neurology Neurological adverse events post-vaccination
Table 1. Neurological adverse events per 100,000 vaccinations with symptoms in infants aged 0 – 2 years
Adverse events Age DTAP DTP FLU3 HEP HIBV IPV MENB MMR PNC PNC13
(AEs) (year)
Recommended 0 2, 4, and 6 See DTAP 6 mo. Birth and 2 and 4 mo. 2, 4, and 2, 4, and 2, 4, and 6 mo.
dosing mo. 1 – 2 mo. 6 – 18 mo. 6 mo.
1 15 – 18 mo. See DTAP 24 mo. 6 – 18 mo. 12 – 15 mo. 6 – 18 mo. 12 – 15 mo. 12 – 15 mo. 12 – 15 mo.
VAERS shots 0 14,496 13,133 1,859 14,616 31,980 13,316 1,687 980 15,681 14,579
with symptoms 1 13,940 4,351 3,166 2,884 17,024 4,398 621 30,890 8,069 6,421
2 2,557 761 1,016 802 1,858 809 252 2,208 1,023 844
Pyrexia (fever) 0 27,794 42,382 26,573 27,107 31,482 29,716 37,759 26,939 29,144 22,388
1 28,615 64,054 26,374 38,592 39,433 34,538 42,351 41,489 32,606 30,649
2 19,398 56,636 17,028 25,935 29,279 24,475 34,921 33,877 24,536 18,009
Abnormal 0 938 198 646 691 722 698 711 2,143 797 1,008
behavior 1 1,083 345 1,011 1,942 999 1,023 483 1,984 868 1,090
2 1,291 394 984 2,244 1,346 742 397 2,174 684 1,777
Aphasia 0 248 61 108 151 125 120 <59 1,633 83 158
1 574 437 632 589 693 455 322 1,172 359 716
2 391 131 98 499 646 124 <397 1,132 196 237
Autism spectrum 0 911 343 538 937 416 623 119 5,102 332 316
disorder 1 1,198 1,402 600 2,774 1,416 1,342 322 3,373 1,115 716
2 1,212 657 197 3,616 1,507 1,607 <397 4,982 978 711
Coordination 0 124 69 <54 103 59 75 59 612 38 48
abnormal 1 323 735 158 728 435 477 <161 702 359 140
2 117 394 492 873 431 371 <397 272 293 237
Encephalopathy 0 373 449 108 356 288 345 178 306 293 192
1 201 253 190 416 241 227 161 282 211 187
2 117 394 98 499 54 247 <397 272 <98 355
Encephalitis 0 366 297 108 322 266 368 296 612 166 254
1 158 161 126 277 282 227 161 450 335 265
2 274 263 197 499 161 494 397 136 293 <118
Febrile 0 1,462 1,432 4,034 1,368 1,401 1,675 9,959 2,959 1,422 1,907
convulsion 1 4,340 6,964 7,960 4,161 5,645 5,070 16,264 5,442 4,722 5,996
2 1,643 2,760 3,543 2,244 2,799 2,843 17,460 3,125 1,369 3,791
Meningitis 0 724 777 54 472 810 691 830 306 784 357
1 136 322 32 208 499 250 322 207 273 234
2 156 263 98 <125 1,722 <124 397 136 587 118
Nervous system 0 345 168 215 397 219 293 <59 1,327 249 144
disorder 1 222 161 95 1,110 229 250 <161 223 186 93
2 235 <131 98 1,372 215 124 <397 91 391 <118
Seizure 0 8,471 9,564 7,208 7,198 7,364 8,073 7,469 4,388 6,875 5,563
1 6,227 16,617 6,822 8,599 9,034 7,071 7,246 7,595 6,556 5,669
2 3,324 14,060 4,429 4,988 6,512 4,326 5,556 6,612 3,617 3,673
Speech disorder 0 531 442 108 684 313 421 <59 2,143 230 219
1 710 712 221 1,144 746 750 161 1,437 632 327
2 548 526 394 1,372 969 494 1,587 1,630 196 829
Staring 0 1,794 129 753 718 1,001 1,540 1,304 816 1,786 1,571
1 832 92 758 728 717 955 483 903 1,029 1,028
2 665 <131 295 249 538 1,112 397 725 880 474
Syncope 0 1,621 921 699 1,232 1,185 1,975 5,453 1,122 1,817 1,687
1 725 850 442 832 723 1,364 4,026 864 768 1,168
2 548 1,183 1,181 998 646 742 2,778 951 782 592
Note: Neurological AE frequency greater than 1,000 are in bold. Abbreviation: mo.: Months.
Volume 3 Issue 1 (2024) 6 https://doi.org/10.36922/an.2258
