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Advanced Neurology LBD prevalence and incidence in India

Figure 1. PRISMA flow chart

4. Discussion We observed a difference in the prevalence between
the three studies reporting DLB or LBD prevalence. Alladi
Our systematic review identified four studies reporting the et al. reported that DLB represented 8.9% of patients with
prevalence of LBD in India, which included 103 participants dementia in a memory clinic in Hyderabad; Banerjee
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with LBD. We used a range of study designs, settings, et al. reported that DLB comprised 1.0% of subjects with
and diagnostic criteria, and no two studies adopted the dementia in a community-based survey in Kolkata; and
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same diagnostic criteria for defining DLB, PDD, or LBD. Patel reported 2.4% of subjects in a clinical population
Furthermore, the tools used to support diagnosis – notably in Karamasad. However, this variation in prevalence
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psychometric scales and biomarkers – differed greatly is not uncommon; a 2014 systematic review of DLB
between the two studies, precluding comparison. One prevalence identified studies reporting that DLB
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unifying characteristic was that all studies were conducted comprised between 0.0% and 24.0% of all dementia
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in urban populations. cases. The same systematic review also identified that
Volume 3 Issue 4 (2024) 4 doi: 10.36922/an.4098