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Advanced Neurology The South London Stroke Register

Figure 3. Age-adjusted rates of outcome per 1000 stroke survivors, with 95% pointwise confidence intervals (Open Access Source).
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Abbreviation: HADS: Hospital Anxiety and Depression Scale; SF 12: Short Form-12 (measure of health-related quality of life).
around 30% of stroke survivors and was associated with thrombolysis and improved functional outcome and long-
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lack of family support, inability to work and functional term survival. 23,24
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dependence. Over 20% of stroke survivors experienced Finally, the SLSR cohort served as a sampling frame for
cognitive impairment, but appropriate vascular risk clinical trials and social science research. A randomised
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management reduced this risk. 21 controlled trial provided evidence that outcomes following
The SLSR has provided real-world, population-based early supported discharge (ESD) were comparable
data on the provision and effectiveness of acute care, to conventional care, whereas length of hospital stay
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reporting substantial improvements: brain imaging was substantially reduced. ESD has since become a
rates increased from 85.2% in 1995 – 1997 to 99.6% in cornerstone of evidence-based stroke management.
2007 – 2009, whereas stroke unit admission increased 6. Translating research into changes in
from 18.9% to 78.4% and median length of hospital
stay decreased from 21 to 31 days. Thrombolysis rates guidelines, policy and service provision
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reached 13.9% in 2005 – 2015. SLSR analyses showed an Data and analyses from the SLSR have yielded a significant
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association between evidence-based acute interventions, impact by effectively translating into both local and
such as stroke unit admission, acute-phase aspirin and national policies for stroke and stroke survivors.

Volume 4 Issue 1 (2025) 76 doi: 10.36922/an.4771