Page 27 - ARNM-2-2

Advances in Radiotherapy
& Nuclear Medicine Melanoma brain metastatic treatment

doi: 10.1093/neuonc/not114 modulation of blood-brain barrier permeability to enhance
drug delivery. Neuro Oncol. 2016;18(12):1601-1609.
14. Brown PD, Gondi V, Pugh S, et al. Hippocampal avoidance
during whole-brain radiotherapy plus memantine for doi: 10.1093/neuonc/now137
patients with brain metastases: Phase III trial NRG oncology 25. Petrelli F, De Stefani A, Trevisan F, et al. Combination of
CC001. J Clin Oncol. 2020;38(10):1019-1029.
radiotherapy and immunotherapy for brain metastases:
doi: 10.1200/JCO.19.02767 A systematic review and meta-analysis. Crit Rev Oncol
Hematol. 2019;144:102830.
15. Long GV, Atkinson V, Lo S, et al. Combination nivolumab
and ipilimumab or nivolumab alone in melanoma brain doi: 10.1016/j.critrevonc.2019.102830
metastases: A multicentre randomised phase 2 study. Lancet 26. He Q, Zhang C, Tang S, Li J, Ren Q. Intracranial radiotherapy
Oncol. 2018;19(5):672-681.
with or without immune checkpoint inhibition for brain
doi: 10.1016/S1470-2045(18)30139-6 metastases: A systematic review and meta-analysis. Transl
Cancer Res. 2020;9(10):5909-5924.
16. Tawbi HA, Forsyth PA, Algazi A, et al. Combined nivolumab
and ipilimumab in melanoma metastatic to the brain. N Engl doi: 10.21037/tcr-20-902
J Med. 2018;379(8):722-730.
27. Najafi M, Jahanbakhshi A, Gomar M, et al. State of the Art
doi: 10.1056/NEJMoa1805453 in combination immuno/radiotherapy for brain metastases:
Systematic review and meta-analysis. Curr Oncol.
17. Petrelli F, Signorelli D, Ghidini M, et al. Association of 2022;29(5):2995-3012.
steroids use with survival in patients treated with immune
checkpoint inhibitors: A systematic review and meta- doi: 10.3390/curroncol29050244
analysis. Cancers. 2020;12(3):546.
28. Su Z, Zhang L, Xue S, Wang Y, Ding R. Comparison of
doi: 10.3390/cancers12030546 immunotherapy combined with stereotactic radiotherapy and
targeted therapy for patients with brain metastases: A systemic
18. Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF review and meta-analysis. Open Life Sci. 2023;18(1):20220559.
gene in human cancer. Nature. 2002;417(6892):949-954.
doi: 10.1515/biol-2022-0559
doi: 10.1038/nature00766
29. Kim PH, Suh CH, Kim HS, et al. Immune checkpoint
19. Davies MA, Saiag P, Robert C, et al. Dabrafenib plus inhibitor with or without radiotherapy in melanoma
trametinib in patients with BRAFV600-mutant melanoma patients with brain metastases: A systematic review and
brain metastases (COMBI-MB): A multicentre, multicohort, meta-analysis. Korean J Radiol. 2021;22(4):584.
open-label, phase 2 trial. Lancet Oncol. 2017;18(7):863-873.
doi: 10.3348/kjr.2020.0728
doi: 10.1016/S1470-2045(17)30429-1
30. Trapani S, Manicone M, Sikokis A, et al. Effectiveness and
20. Shiao SL, Coussens LM. The tumor-immune safety of “real” concurrent stereotactic radiotherapy and
microenvironment and response to radiation therapy. immunotherapy in metastatic solid tumors: A systematic
J Mammary Gland Biol Neoplasia. 2010;15(4):411-421.
review. Crit Rev Oncol Hematol. 2019;142:9-15.
doi: 10.1007/s10911-010-9194-9
doi: 10.1016/j.critrevonc.2019.07.006
21. Ashrafizadeh M, Farhood B, Eleojo Musa A, Taeb S, Rezaeyan 31. Chen L, Douglass J, Kleinberg L, et al. Concurrent immune
A, Najafi M. Abscopal effect in radioimmunotherapy. Int checkpoint inhibitors and stereotactic radiosurgery for
Immunopharmacol. 2020;85:106663.
brain metastases in non-small cell lung cancer, melanoma,
doi: 10.1016/j.intimp.2020.106663 and renal cell carcinoma. Int J Radiat Oncol Biol Phys.
2018;100(4):916-925.
22. Alvarez JI, Saint-Laurent O, Godschalk A, et al. Focal
disturbances in the blood-brain barrier are associated with doi: 10.1016/j.ijrobp.2017.11.041
formation of neuroinflammatory lesions. Neurobiol Dis. 32. Badrigilan S, Meola A, Chang SD, et al. Stereotactic
2015;74:14-24.
radiosurgery with immune checkpoint inhibitors for
doi: 10.1016/j.nbd.2014.09.016 brain metastases: A meta-analysis study. Br J Neurosurg.
2023;37(6):1533-1543.
23. Procureur A, Simonaggio A, Bibault JE, Oudard S,
Vano YA. Enhance the immune checkpoint inhibitors doi: 10.1080/02688697.2021.2022098
efficacy with radiotherapy induced immunogenic cell death: 33. Kiess AP, Wolchok JD, Barker CA, et al. Stereotactic
A comprehensive review and latest developments. Cancers. radiosurgery for melanoma brain metastases in patients
2021;13(4):678.
receiving ipilimumab: Safety profile and efficacy of combined
doi: 10.3390/cancers13040678 treatment. Int J Radiat Oncol Biol Phys. 2015;92(2):368-375.
24. Appelboom G, Detappe A, LoPresti M, et al. Stereotactic doi: 10.1016/j.ijrobp.2015.01.004

Volume 2 Issue 2 (2024) 7 doi: 10.36922/arnm.3499