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Advances in Radiotherapy
& Nuclear Medicine Influence of photon beam quality in radiotherapy

A B C

D E F

Figure 3. The mean inhomogeneity correction factors (ICFs) plotted against the beam quality index for three-dimensional conformal radiotherapy
treatment plans: (A and B) represent lung cases, (C and D) represent gynecology, and (E and F) represent prostate cases. The absolute ICF values have been
normalized using the reference beam qualities of 0.670 for 6 MV and 0.760 for 15 MV.

plans compared to other treatment sites. Nevertheless, this
variation is not deemed clinically significant. This study
underscores the importance of accurately determining
ICFs during treatment planning, particularly for lung
tumors, given the complex interplay between beam quality
and ICFs. This study highlights the necessity for precise
beam quality measurements to ensure consistent and
effective dose delivery across different types of tumor and
treatment sites.

Acknowledgments
We extend our acknowledgments to the colleagues of
Medical Physics Department of the Maria Sklodowska-
Curie National Research Institute of Oncology, Warsaw,
Poland. Their exceptional supports with resources,
technical expertise, and spirit of cooperation have been
Figure 4. The mean inhomogeneity correction factors as a function of the pivotal to the successful completion of the study.
beam quality index for lung stereotactic body radiation therapy treatment
plans using 6 MV and 6 MV flattening filter-free photon beams Funding
None.
between dose calculation algorithms could lead to dose
distribution variations of up to 10.0%. 22 Conflict of interest
The authors declare that they have no competing interests.
4. Conclusion

The effect of energy variations (TPR 20,10 ) on ICFs was Author contributions
found to be more significant in lung 3DCRT treatment Conceptualization: All authors

Volume 3 Issue 2 (2025) 89 doi: 10.36922/arnm.6851