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Brain & Heart Cerebral ischemia biomarkers

polymorphisms with recurrent ischemic stroke in two 958.
different Asian populations: A case-control study. Neurol 67. del Zoppo GJ, Hallenbeck JM. Advances in the vascular
Sci. 2019;40(7):1347-1354.
pathophysiology of ischemic stroke. Thromb Res.
56. Traylor M, Farrall M, Holliday EG, et al. Genetic risk 2000;98(3):73-81.
factors for ischemic stroke and its subtypes: A meta- doi: 10.1016/s0049-3848(00)00218-8
analysis of genome-wide association studies. Lancet Neurol.
2019;18(12):1062-1073. 68. Basu S, Rickards CA, Forbes JM, et al. Oxidative stress,
ischemic stroke, and neurodegenerative diseases:
57. Martínez-Miguel P, Albalate M, Durán-Laforet V, et al.
Effective glutamate clearance from the systemic circulation A translational perspective. Oxid Med Cell Longev.
by hemodialysis: Potential relevance for cerebral ischemia 2021:6655649.
management. Artif Organs. 2021;45(10):1183-1188. 69. Radenovic L, Nenadic M, Ułamek-Kozioł M, et al.
Heterogeneity in brain distribution of activated microglia
doi: 10.1111/aor.13933
and astrocytes in a rat ischemic model of Alzheimer’s
58. Selakovic V, Korenic A, Radenovic L. Spatial and temporal disease after 2 years of survival. Aging (Albany NY).
patterns of oxidative stress in the brain of gerbils submitted 2020;12(12):12251-12267.
to different duration of global cerebral ischemia. Int J Dev
Neurosci. 2011;29(6):645-654. doi: 10.18632/aging.103411
70. Shi K. TREM2 exerts neuroprotective effects in traumatic
doi: 10.1016/j.ijdevneu.2011.02.009
brain injury via suppression of inflammatory activation and
59. Alrafiah A, Alofi E, Almohaya Y, et al. Angiogenesis microglial-meditated neuronal apoptosis. Neurosci Lett.
biomarkers in ischemic stroke patients. J Inflamm Res. 2019;723:131076.
2021;14:4893-4900.
71. Puentes F. CD11b immunolabeling as a reliable method to
doi: 10.2147/JIR.S331868 quantify microglia activation and distribution in human
60. McCabe JJ, Walsh C, Gorey S, et al. C-reactive protein, ischemic stroke’s adult and neonatal cerebral infarcts. R Rep.
interleukin-6, and vascular recurrence after stroke: 2018;3(196):1-3.
An individual participant data meta-analysis. Stroke. 72. Xing. AMP-activated protein kinase (AMPK) oscillates
2023;54(5):1289-1299. microglia inflammation to alleviate neuronal apoptosis
doi: 10.1161/STROKEAHA.122.040529 via the AMPK/AKT/NF-κB signal pathway. FASEB J.
2021;35(9):e21883.
61. Burger PM, Pradhan AD, Dorresteijn JAN, et al. C-reactive
protein and risk of cardiovascular events and mortality in 73. Pluta R, Jabłoński M. Exosomes in post-ischemic brain. In:
patients with various cardiovascular disease locations. Am J Pluta R, editor. Cerebral Ischemia. Ch. 6. Brisbane, AU: Exon
Cardiol. 2023;197:13-23. Publications; 2021.
62. Chen L, Xu M, Huang Q, Wen C, Ren W. Lactate 74. Xie R, Zeng X, Yan H, Huang X, Deng C. Effects and
dehydrogenase predicts hemorrhagic transformation mechanisms of exosomes from different sources in cerebral
in patients with acute ischemic stroke. Gerontology. ischemia. Cells. 2022;11(22):3623.
2023;69(5):571-580. doi: 10.3390/cells11223623
doi: 10.1159/000528951 75. Tian T, Zhang HX, He CP, et al. Surface functionalized
63. Henriques DP. Blood pressure variability and cerebrovascular exosomes as targeted drug delivery vehicles for cerebral
regulation in acute ischemic stroke: Approach and future ischemia therapy. Biomaterials. 2018;150:137-149.
directions. Front Neurol. 2021;12:662374. doi: 10.1016/j.biomaterials.2017.10.012
64. Sekeljic V, Bataveljic D, Stamenkovic S, et al. Cellular 76. Selakovic V, Raicevic R, Radenovic L. Temporal patterns
markers of neuroinflammation and neurogenesis after of soluble adhesion molecules in cerebrospinal fluid and
ischemic brain injury in the long-term survival rat model. plasma in patients with the acute brain infraction. Dis
Brain Struct Funct. 2012;217(2):411-420. Markers. 2009;26(2):65-74.
doi: 10.1007/s00429-011-0336-7
doi: 10.3233/DMA-2009-0608
65. Pluta R, Januszewski S, Czuczwar SJ. Neuroinflammation in 77. Salgado JV, Casolla B, Rossipal R, et al. Vascular cell
post-ischemic neurodegeneration of the brain: Friend, foe, adhesion molecule-1 as biomarker in Alzheimer’s disease
or both? Int J Mol Sci. 2021;22(9):4405. and cerebrovascular ischemia. Aging Dis. 2019;10(6):1302-
doi: 10.3390/ijms22094405 1311.
66. Chen Z, Wang B, Miao Y, et al. The emerging role of MCP-1 78. Liu F, Gao Y, Liu L, et al. ICAM-1, VCAM-1, and
in cerebral ischemia and stroke. Aging Dis. 2021;12(3):944- E-selectin expression in leukocytes and aortic endothelial

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