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Brain & Heart Digital tools for stroke and bleeding risk in AF

10 (male) and 12 (female). As per CHA2DS2-VASc. Hematocrit, hemoglobin, and mean corpuscular hemoglobin As per CHA2DS2-VASc. Platelet count and mean platelet Other CBC: white blood cell count and red cell distribution width. Other BMP: sodium, potassium, bicarbonate, calcium, and glucose. IMRS uses sex-specific values.

IMRS‑VASc (2019) ✔ Serum creatinine. concentration. volume. ✔ ✔ ✔

GARFIELD‑AF (2017) 10 ✔ Diastolic BP. Moderate-to-severe CKD stage III – IV. ✔ ✔ ✔ History of heart failure or LVEF <40%. Current tobacco use, dementia, and history of CAD and PAD.

ABC (2016) 4 Increasing points ≥60 years old. ✔ Increasing points for NTproBNP >50. Increasing points for high-sensitivity troponin.
Table 1. Factors used in various scoring systems for assessing stroke risk in patients with atrial fibrillation (AF)

ATRIA Stroke (2013) 8 Eight categories of age+stroke history: 65 – 74; 75 – 84; and≥85. Increasing points for patients with older age and prior stroke. ✔ Two variables: (i) eGFR <45 by MDRD equation or ESRD; (ii) proteinuria: urine dipstick protein≥1+ (≥30 mg/dL) without urinary tract infection. ✔ ✔ ✔ ✔ Abbreviations: BMP: Basic metabolic panel; BP: Blood pressure; CAD: Coronary artery disease; CBC: Complete blood count; CKD:

CHA 2 DS 2 ‑VASc (2010) 7 65 – 74 years: 1 point; ≥75 years old: 2 points. ✔ History of vascular disease, including stroke, MI, PAD, or aortic plaque. ✔ ✔ Recent CHF exacerbation. No LVEF criterion.

Framingham (2003) 5 Increasing risk points for age groups >60. Increasing points for every 10 mmHg above 120 mmHg systolic BP. ✔ ✔ ✔ peptide; PAD: Peripheral artery disease; TIA: Transient ischemic attack; ✔: Variable used in scoring.

CHADS 2 (2001) 5 ≥75 years old. Any history of hypertension (no BP cutoff defined). Stroke or TIA symptoms. ✔ Recent CHF exacerbation. No LVEF criterion.

Factors Number of variables Old age Diagnosed hypertension Renal disease Bleeding history Anemia Prior stroke or TIA Platelets Female sex Diabetes mellitus Heart failure Additional factors

Volume 2 Issue 3 (2024) 3 doi: 10.36922/bh.3068