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Eurasian Journal of Medicine and
            Oncology
                                                                                        Integrative prophetic medicine


            increasingly supporting the benefits of these treatments.   Researchers have identified several active components
            As of March 2024, a search of PubMed, a major medical   within the seed, including thymoquinone, which is safe in
            research database, revealed a significant number of studies   clinical trials. 41-43  The potential antiviral properties of N.
            on common PM therapies: olive oil (4,622), honey (3,122),   sativa are noteworthy; studies, including those focused on
            black seed (1,255), vinegar (1,015),  N. sativa (another   coronaviruses, suggest that the seed may help combat viral
            term for black seed, 1,014), and cupping therapy (959), as   infections and reduce viral load. 44-48  In addition, the seed
            presented in Table 1.                              possesses immune-boosting effects, helping the body to
                                                               fight infections. 49,50  Interestingly, N. sativa can also act as
            4. PM: An IM model                                 an anti-inflammatory agent, reducing inflammation under

            IM seeks to synergistically amalgamate conventional   various conditions. Other reported benefits include pain
            medicine with CAM modalities. Within this paradigm,   relief, fever reduction, and bronchodilation. 51,52
            numerous investigations have examined the therapies   Studies have also shown that  N.  sativa may provide
            associated with PM. While empirical evidence supporting   cardiovascular protection by shielding the heart from
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            the efficacy of all PM therapies remains limited, certain   the harmful effects of reactive oxygen species, potentially
            modalities demonstrate potential as adjunctive interventions.   reducing heart damage and complications associated with
            These therapies may offer ancillary benefits by mitigating   high blood pressure.  N. sativa shows promise  in cancer
            adverse effects, such as fatigue, nausea, and pain. 38,39  This   research; a key component – the dark pigment of the seed coat
            suggests that selected, well-substantiated PM practices   (herbal melanin) – has been shown to inhibit the proliferation
            could serve as suitable candidates for the development of an   of acute monocytic leukemia cells.  In addition, N. sativa has
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            IM model. This section will outline the most scientifically   shown  potential  in  inducing  apoptosis  in  lymphoma  cells,
            validated PM practices within each component of PM.  suggesting therapeutic applications for certain cancers. 54

            4.1. Herbal and food therapy                       4.1.2. Honey
            Numerous prophetic traditions reference the beneficial   Honey, a natural sugary liquid packed with nutrients, has
            properties of over 60 botanicals and food items. Within the   long been celebrated for its health benefits.  Research shows
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            domain of PM, certain herbs assume paramount importance,   that honey contains unique antioxidants and possess distinct
            captivating considerable scientific scrutiny. A diverse array of   antibacterial properties. Clinical studies suggest that honey
            scholars, including botanists, biochemists, natural product   may outperform modern wound dressings due to its healing
            specialists, and medical researchers, are keenly interested in   effects and antimicrobial properties. 56,57  In particular,
            exploring the multifaceted aspects of these botanicals. Their   reviews have demonstrated that honey is effective in treating
            investigations encompass a comprehensive exploration   venous ulcers, with patients reporting positive outcomes. 58
            of their therapeutic potential, their capacity to enhance
                                                                 In addition, honey acts as a prebiotic, promoting the
            overall well-being, and the identification of the bioactive   growth of beneficial gut bacteria, such as  Lactobacillus
            constituents responsible for their unique properties.  This   and  Bifidobacterium, which may help alleviate various
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            section will focus on a selected group of “prophetic herbs”          59
            that have garnered substantial scientific attention.  gastrointestinal issues.  Studies have shown that the
                                                               antioxidant  and  antimicrobial  properties  of  honey
            4.1.1. Black seeds                                 can soothe coughs and improve sleep in children and
                                                               adults at a dosage of 2.5  mL.  Honey may also help in
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            N. sativa, a seed with a long history of culinary and   managing gastroesophageal reflux disease by coating
            medicinal use, is garnering renewed scientific interest.
                                                               the esophagus and stomach lining, thereby reducing
                                                               acid reflux. Furthermore, it promotes tissue repair in the
            Table 1. References on prophetic medicine therapies
            identified through a PubMed search (March 2024)    sphincter  muscle,  preventing  acid  from  backing  up.  In
                                                               addition, a clinical study suggested that honey can lower
            Prophetic medicine treatment    Number of citations  bad cholesterol levels and prevent blood sugar spikes in
            Olive oil                            4,622         individuals with high cholesterol. Some research even
            Honey                                3,122         indicates that honey may have the potential to prevent
            Black seed                           1,255         cancer by inhibiting cancer development. 61,62
            Vinegar                              1,015         4.1.3. Dates
            Nigella sativa                       1,014         The date palm is often referred to as the “tree of life” and
            Cupping therapy                       959          is valued  for its delicious fruits. These nutritious fruits


            Volume 9 Issue 1 (2025)                         49                              doi: 10.36922/ejmo.6765
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