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Eurasian Journal of Medicine

                                                                                    and Oncology





                                        LETTER TO EDITOR
                                        Potential applications of green prescription of

                                        Chinese medicine in rheumatoid arthritis



                                        Yan Zhang  and Ligang Jie*
                                        Department of Rheumatology and Clinical Immunology, Zhujiang Hospital, Southern Medical
                                        University, Guangzhou, China




                                        Dear Editor,
                                        Rheumatoid arthritis (RA) is an autoimmune disease characterized by persistent
                                        synovial inflammation, joint destruction, and systemic complications that severely affect
                                        patients’ quality of life. Epidemiological study has suggested that there are approximately
                                        17.6 million RA patients worldwide,  and the total economic cost attributed to the disease
                                                                    1
                                        is estimated to be between US$2,408 and US$83,845/year,  placing a heavy economic
                                                                                       2
                                        burden on patients, families, and society. Disease-modifying antirheumatic drugs and
                                        glucocorticoids are both common drugs used to treat RA, but long-term use can cause
                                        a variety of adverse reactions.  The efficacy of complementary non-pharmacological
                                                                3,4
                                        strategies has gained increasing recognition in contemporary RA management
                                        paradigms. The American College of Rheumatology now explicitly recognizes structured
                                        exercise and nutritional adjustments as foundational treatment elements in its revised
                                        clinical guidelines.  The proposed intervention aligns with green prescription paradigms,
                                                      5
                                        an innovative healthcare strategy initiated in New Zealand’s medical reforms during the
                                        late 20  century.  Clinical validation has confirmed the therapeutic value of evidence-
                                                     6
                                             th
                                        informed programs in modulating inflammatory processes, optimizing metabolic
                                        regulation, and promoting psychological well-being among chronic disease populations.
                                                                                                             7
            *Corresponding author:      The Chinese Medicine Green Prescription (GPCM) framework operationalizes this
            Ligang Jie
            (jieligang1976@smu.edu.cn)  concept through systematic integration of historically rooted movement therapies with
                                        modern dietary protocols and biomedical interventions. Featuring traditional medical
            Citation: Zhang Y, Jie L. Potential   principles harmonized with contemporary rehabilitation methodologies, this combined
            applications of green prescription
            of Chinese medicine in rheumatoid   therapeutic model demonstrates clinically validated outcomes as an adaptable and
            arthritis. Eurasian J Med Oncol.   economically viable approach to RA management.
            2025;9(2):287-289.
            doi: 10.36922/EJMO025100049   Some studies have demonstrated the therapeutic potential of traditional Chinese
            Received: March 8, 2025     exercise therapy regimens in RA management, exhibiting multidimensional therapeutic
                                        impacts beyond articular functional enhancement and quality of life improvement to
            Accepted: March 11, 2025    psychological state modulation. Traditional Chinese exercises including Taijiquan,
            Published online: March 27, 2025  Baduanjin,  and  Yijin  Jing  enhance  local  circulation  by  coordinating  movement-
            Copyright: © 2025 Author(s).   breathing patterns. Clinical trials suggest that these practices may improve joint
            This is an Open-Access article   function, mental health, and immune regulation in RA patients. A controlled clinical
            distributed under the terms of the   investigation revealed that structured Yijin Jing practice significantly augmented manual
            Creative Commons Attribution
            License, permitting distribution,   dexterity, grip capacity, and joint mobility while concurrently elevating life quality
            and reproduction in any medium,   metrics and mitigating anxiety-depression scores, without engendering adverse effects
            provided the original work is   on joint inflammation in RA patients.  In addition, Du et al. found that Tai Chi exercise
                                                                      8
            properly cited.
                                        combined with hand exercise is an effective treatment for RA that can improve joint pain,
            Publisher’s Note: AccScience   disease activity, quality of life, depression, and anxiety.  The study would be extended to
                                                                                   9
            Publishing remains neutral with
            regard to jurisdictional claims in   further optimize the intervention program of traditional Chinese exercise and conduct
            published maps and institutional   larger pre-clinical and clinical trials to clarify its pharmacological mechanism and
            affiliations.
            Volume 9 Issue 2 (2025)                        287                         doi: 10.36922/EJMO025100049
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