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Global Health Econ Sustain                                          Quantum Data Lake for epidemic analysis




            Table 5. (Continued)                               PT-symmetry. PT-symmetry is distinct from the condition
                                                               of Hermiticity, creating a new kind of quantum theory
            Identifier         Disease and symptoms            with continuation from real-symmetric Hamiltonians to
            In2     Oropharyngeal infection associated with head and neck SCC  complex Hamiltonians (Bender et al., 2003; Bender, 2003;
            In3     Oral cavity infections associated with oropharyngeal cancer  Bender, 2005; Bender et al., 2005a; Bender, 2007; Bender
            In4     Sporadic infections in mucocutaneous tissue  & Darg, 2007; Bender et al., 2013; Bender, 2015; Bender
            In5     Children with diarrhea                     et al., 2017; Bender  et al., 2018; Bender, 2020; Bender
            In6     Cervical infection                         et al., 2021). A Hamiltonian is a Dirac Hermitian, and its
            In7     Febrile respiratory syndrome               energy eigenvalues are always real. As indicated by Bender,
            W1      Common warts (verruca vulgaris)            a Dirac Hermitian Hamiltonian cannot have a phase
                                                               transition where its eigenvalues go from real to complex.
            W2      Flat warts (verruca planae)                However,  PT-symmetric  Hamiltonians  have  two  regions
            W3      Plantar warts                              regarding real energy parameter ε – a region of unbroken
            W4      Mosaic warts                               PT-symmetry (ε ≥ 0), where the eigenvalues are all real,
            W5      Anogenital warts (condyloma acuminata)     and a region of spontaneously broken PT-symmetry (ε < 0),
            W6      Butcher’s warts                            where real eigenvalues transform to the complex plane as
            W7      Bowenoid papulosis                         complex conjugate pairs. If a Hamiltonian has an unbroken
            W8      Cystic non-genital warts (plantar epidermoid cysts)  PT-symmetry, every eigenstate of the PT-symmetric
                                                               non-Hermitian operator satisfies the PT-symmetry,
            W9      Deep palmoplantar warts (myrmecia)         and the energy levels are real and positive; the time-
            W10     Palmoplantar pigmented warts with homogeneous   evolution operator e -iHt/ħ  is unitary without violating any
                    intracytoplasmic inclusion bodies          of the physical axioms of quantum mechanics. If the
            No1     No indication                              PT-symmetry is spontaneously broken, some eigenstates
            No2     Detection on normal skin                   do not correspond to the eigenstates of the PT operator,
            No3     Detection on normal genital area           and some pairs of eigenvalues become complex conjugate
            No4     Asymptomatic presence in healthy human     to each other. PT-symmetric non-Hermitian Hamiltonians
            No5     Detection on sun-exposed skin              with complex potentials are denoted by Equations VII and
            No6     Detection in the oropharynx of healthy human  VIII.
            S1      WHIM syndrome                              H = H PT                                  (VII)
            S2      Asymptomatic presence in Merkel cell carcinoma patients   H  = p  + x  (ix)         (VIII)
                                                                        2
                                                                PT
                                                                            ε
                                                                     2
                    (skin tumor, Human polyomavirus 5)
            S3      Psoriatic lesions                            Bender  et al.  explained  that  PT-symmetric  systems
            S4      Pruritic and dyskeratotic dermatoses       are intermediate between open (contact with an external
                                                               environment) and closed (isolated) systems. The unbroken
            S5      Asymptomatic presence in HIV/AIDS patients  PT-symmetry phase is in equilibrium and mimics a
            S6      Asymptomatic presence in GATA2 deficiency patient  closed system. The broken PT-symmetry phase is in non-
            S7      Punctate palmoplantar keratoderma          equilibrium, mimics an open system, and is characterized
            S8      Glans lichen sclerosus                     by loss to or gain from its environment. The boundary
            Abbreviations: AIDS: Acquired immunodeficiency syndrome,   between these two regions corresponds to a phase
            ASC-US: Atypical squamous cells of undetermined significance,    transition (real-to-complex spectral transition) that is
            CIN: Cervical intraepithelial neoplasia, HIV: Human   called an exceptional point (or Bender-Wu singularity).
            immunodeficiency virus, HPV: Human papillomavirus,
            HSIL: High-grade squamous intraepithelial lesion, LSIL: Low-grade   The phase transition with an exceptional point is of great
            squamous intraepithelial lesion, SCC: Squamous cell carcinoma,   interest for epidemic modeling.
            VIN: Vulvar and vaginal intraepithelial neoplasia, WHIM: Warts,
            hypogammaglobulinemia, immunodeficiency, and myelokathexis.  3. Discussion
                                                               3.1. Epidemic data complex structure
            & Boettcher in 1998 (Bender & Boettcher, 1998). Since
            then, this theory has been elaborated by Bender  et al.,   Epidemic data have a very complex structure and the
            demonstrating an alternative to the axiom of standard   highest possible range of diversity. Raw data for epidemic
            quantum mechanics that the Hamiltonian must be     modeling  are  characterized  by  multidimensionality  and
            Hermitian. The axiom of Hermiticity may be replaced by   uncertainty. While processing epidemic data, the machine’s
            the physical condition of space-time reflection symmetry or   rational, logical output inevitably comes into direct conflict


            Volume 2 Issue 1 (2024)                         15                       https://doi.org/10.36922/ghes.2148
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