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Global Health Econ Sustain                                          Quantum Data Lake for epidemic analysis



                                                                 Notably, in a study by Upham et al. (2021), the problem
                                                               of disconnected data about viruses was raised. The authors
                                                               emphasized that there was accumulating information
                                                               particularly related to host-virus interaction, but the
                                                               taxonomic data remained “dark” and very scattered,
                                                               thereby being of no significant value. Data can be valuable
                                                               for epidemic forecasting and control, provided that the
                                                               different data flows are interconnected on a massive
                                                               scale. Massad  et  al. (2003) asserted that the problem
                                                               of uncertainty is the most critical in epidemiology and
                                                               medicine; the authors divided uncertainty in epidemiology
                                                               into two types: Stochasticity and lack of knowledge.
                                                               According to viral infections, a single symptom may appear
                                                               in the presence of a very wide range of viruses and may be
                                                               presented across different diseases. Uncertainty is evident
                                                               through the presentation of the opposing health and disease
            Figure  2.  The complex interaction in the triple nexus system   states. For example, the asymptomatic presence of a virus
            (i.e., environmental, social, and immune aspects) affecting the circulation   or several different viruses could result in an unclear health
            of viruses.                                        state despite the risk of disease progression. Therefore, it is
                                                               necessary to formulate a solution to uncertainty, such as
            2011). The algorithm “Uniform Manifold Approximation   further validation with laboratory methods to confirm that
            and  Projection”  was  created  based  on  Riemannian   the manifested symptoms are related to a viral infection.
            geometry and used for reconstructing COVID-19
            pandemic propagation with WHO data on the confirmed   Pomorski (2020) investigated the quantum essence of
            cases and deaths globally (McInnes et al., 2020).  epidemic uncertainty, originating from a superposition
                                                               of  health  states.  The  codependence  of  two  probabilities
              The presented DNA virus ontology indicated data   of health states and disease corresponds to a scattering
            uncertainty, multidimensionality, and disconnection   matrix. Pomorski discussed the infection propagation
            in terms of dispersion across data sources, variety and   using  the  quantum  tight-binding  model.  Considering
            similarity of symptoms, the possibility of coinfection with   multidimensionality and uncertainty, Alzeley (2019)
            different combinations of viruses, as well as an infinite   emphasized the advantages of using quantum probability
            number of influencing factors on infection outcome (e.g.,   tools for epidemic modeling, of which one of the variants
            different periods of epidemics occurrence and geographic   is a quantum random walk. Tchapet Njafa & Nana Engo
            differences), thereby affirming the preferential use of the   (2018) presented the model of Quantum Associative
            quantum approach for data exposition, creation of value,   Memory for four tropical diseases (malaria, typhoid fever,
            and modeling. The most sophisticated space corresponding   yellow fever, and dengue) to diagnose a single infection or a
            to multidimensionality and uncertainty is the Hilbert   combined polyinfection. The authors interpreted the model
            space. Quantum solutions are complicated by reliance   in favor of quantum computing based on the main quantum
            on superposition, entanglement, parallelism, quantum
            random walk, quantum tight-binding, and quantum neural   properties: Quantum superposition, entanglement, and
            networks, considering the uncertainty, multidimensionality,   quantum parallelism. The Quantum Associative Memory
            and  data  disconnection.  In  this  regard,  the  quantum   model comprises 14 qubits and can distinguish a single
                                                               infection from a coinfection without a laboratory facility.
            approach can prospectively transform data into value,
            taking into account several key parameters (i.e., time,   León  &  Pozo  (2007)  developed  a  model  based  on
            energy, and symmetry) in epidemic data presentation.  a quantum algorithm to predict the spread of human
                                                               immunodeficiency virus (HIV) infections. Each individual
            3.2. Related works                                 was represented by a qubit, where an infected individual is

            In this section, we elucidate the transition to adopting   represented by state |1⟩ and a non-infected individual is
            quantum approaches in response to the aforementioned   represented by state |0⟩. In an uncertain situation, where
            problems of uncertainty, multidimensionality, and data   an individual is not aware of the infection condition, the
            disconnection within the field of epidemiology. The   individual is considered a superposition. The authors used
            respective authors derived the use of quantum approaches   the Toffoli quantum gate to compute possible interactions
            in the same way as we derived them.                among individuals.  The evolution of the epidemic  was


            Volume 2 Issue 1 (2024)                         18                       https://doi.org/10.36922/ghes.2148
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