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Global Health Econ Sustain                                                  Disparities in cancer outcomes




            Table 4. Univariate associations for estimated age‑standardized cancer incidence in 2020
            Variable                              β           Standard error    95% confidence interval  p
            Health expenditure as a percentage of GDP  3.59   3.44              −3.48; 10.65             0.307
            Universal health coverage service     1.90        1.68              −1.56; 5.37              0.269
            Dedicated funding for early detection program  3.51  4.87           −6.50; 13.52             0.478
            Cancer early detection program        −7.78       16.74             −42.81; 27.26            0.647
            Referral systems                      2.81        12.11             −22.07; 27.70            0.818
            Public and private cancer centers     −0.71       1.73              −4.30; 2.88              0.684
            Abbreviation: GDP: Gross domestic product.

            Table 5. Univariate associations for estimated age‑standardized mortality in 2020

            Variable                              β           Standard error    95% confidence interval  p
            Health expenditure as a percentage of GDP  −5.18  1.56              −8.38; −1.97             0.003
            Universal health coverage service     −2.75       0.74              −4.27; −1.23             0.001
            Dedicated funding for early detection program  0.13  2.61           −5.23; 5.49              0.961
            Cancer early detection program        8.25        8.54              −9.62; 26.12             0.346
            Referral systems                      8.11        6.22              −4.68; 20.90             0.204
            Public and private cancer centers     −1.05       0.78              −2.67; 0.57              0.193
            Abbreviation: GDP: Gross domestic product.

            Table 6. Univariate associations for the estimated number of prevalent cases (5‑year period) in 2020
            Variable                              β           Standard error    95% confidence interval  p
            Health expenditure as a percentage of GDP  3.59   3.44              −3.48; 10.65             0.307
            Universal health coverage service     1.90        1.68              −1.56; 5.37              0.269
            Dedicated funding for early detection program  3.51  4.87           −6.50; 13.52             0.478
            Cancer early detection program        −7.78       16.74             −42.81; 27.26            0.647
            Referral systems                      2.81        12.11             −22.07; 27.70            0.818
            Public and private cancer centers     −0.71       1.73              −4.30; 2.88              0.684
            Abbreviation: GDP: Gross domestic product.

            aims to enhance understanding of the multifaceted factors   both health expenditure as a percentage of GDP and
            influencing cancer outcomes. These findings can potentially   UHC services. These findings suggest that as the values
            inform strategies and policies aimed at optimizing health   (corresponding to health expenditure as a percentage of
            systems and improving overall cancer care and management.  GDP and UHC services) increase, the corresponding age-
                                                               standardized mortality rates tend to decrease. Moreover,
            3.2. Association between health expenditure, UHC,   regression analysis  revealed a  pattern  within  Baltic
            and age-standardized mortality in 2020             European countries (i.e., Latvia, Estonia, and Lithuania),
            When examining the relationship between estimated age-  Southeastern European countries (i.e., Bulgaria, Croatia,
            standardized mortality rates in 2020 and key variables, notable   and Romania), and Central Eastern European countries
            correlations were observed. Specifically, health expenditure as   (i.e., Czechia, Hungary, Poland, Slovakia, and Slovenia),
            a percentage of GDP (p = 0.003) and UHC services (p = 0.001)   indicating higher age-standardized mortality rates in 2020,
            exhibited significant associations. Their unstandardized   alongside lower health expenditure as a percentage of GDP
            coefficients (i.e., β = −5.18 and −2.75, respectively) suggest   and reduced UHC services. This analysis suggests a trend
            that elevated levels of these variables correlate with reduced   toward elevated age-standardized mortality rates within
            estimates of age-standardized mortality in 2020 (Table 5).  these regions.
              Figures  1 and  2 confirm the inverse relationship   Conversely, countries  within continental  Europe
            between age-standardized mortality rates in 2020 and   (including Luxembourg, Austria, Belgium, France,


            Volume 2 Issue 2 (2024)                         5                        https://doi.org/10.36922/ghes.3216
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