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Global Health Econ Sustain                                                  Disparities in cancer outcomes



            5. Conclusion                                      from the IARC based on GLOBOCAN 2020 estimates
                                                               introduces  potential  challenges.  The  accuracy  and
            This study represents a notable achievement as it uncovered   reliability of these estimates are contingent upon the quality
            correlations between essential health system attributes,   and comprehensiveness of the data reported by individual
            particularly the degree of UHC gauged by the UHC Index,   countries. Disparities in data collection methods,
            and the availability of public cancer centers measured by   reporting standards, and health-care infrastructures
            their number per 10,000 individuals diagnosed with cancer.   could impact the robustness of the findings. In addition,
            These factors are identified as predictors for improving   the utilization of country-level data, often sourced from
            cancer mortality rates.                            surveys, presents another constraint. Nevertheless, data
              Based on the extensive dataset, it is indicated that in   curated by the WHO undergoes stringent scrutiny for
            countries where late-stage cancer diagnoses are common, a   accuracy through technical assessments conducted at the
            focused approach toward cancer early detection initiatives   national level.
            should  strive  to  attain  a  target  where  60%  of  invasive   However, reliance on data reported by countries,
            cancers are detected at stage I or II. This threshold emerges   including cancer registration and the oversight of crucial
            as a significant measure for effective cancer downstaging   health system elements, may lead to incomplete or
            efforts.                                           potentially insufficient information in certain instances.
              These discoveries provide substantial direction for   Another limitation arises from possible disparities in the
            the WHO in its worldwide endeavors to enhance cancer   timing of data collection, which introduces complexities
            outcomes.  The  data  emphasizes  the  crucial  influence  of   in the correlational analysis when the data are not
            health system attributes and targeted interventions in   contemporaneous. To mitigate this, the study prioritized
            fostering advancements in cancer mortality rates globally.   the  utilization of  the  most recent  WHO (2020)  reports
            This analysis underscores the vital significance of sufficient   to minimize temporal discrepancies. Furthermore, the
            early detection, combined with prompt access to affordable   analysis concentrates on a specific timeframe (2020) for
            and efficacious cancer treatment, as the fundamental   cancer-related metrics. Cancer outcomes, health-care
            requirement for attaining enduring decreases in cancer   expenditures, and health system attributes may have
            mortality across the globe (Santucci et al., 2020).  evolved over time, and the study does not accommodate
                                                               these temporal fluctuations.
              The 2030 UN SDGs emphasize the significance of
            ensuring universal access to high-quality health-care   The current analysis may not entirely encapsulate shifts
            services without imposing financial burdens. Although   in cancer care and health-care policies, and certain health
            per-capita income typically reflects a country’s UHC Index   system attributes might not precisely reflect real-world
            score, there are discrepancies in performance among   practices within countries. For example, while national-
            countries sharing similar income levels. Effective UHC   level cancer management guidelines may exist, their
            performance is  associated with the  portion of a  nation’s   adherence at the local or subnational level is not guaranteed.
            health-care budget administered through governmental   Likewise, the presence of early detection services does not
            and social health insurance programs.              necessarily  imply  comprehensive  coverage  among  the
                                                               broader population. To address this complexity, the WHO
              The UHC index serves as a metric to monitor progress
            toward SDG indicator 3.8.1 and is based on key interventions   integrates data on the dedicated funding allocated for these
                                                               services—an indicator of their actual implementation.
            related to essential health services, covering reproductive,
            maternal, neonatal, and child health, infectious diseases,   Acknowledgments
            and NCDs, as well as health-care capacity and accessibility.
            Notably, a previous study spanning from 1990 to 2010 across   None.
            79 countries found that increased unemployment correlated   Funding
            with higher mortality rates in aggregated cancers (including
            female breast, prostate, and colorectal cancers) (Duggan   None.
            et al., 2021; Maruthappu  et al., 2016). However, it was
            observed that the implementation of UHC appeared to offer   Conflict of interest
            a protective effect against this correlation, indicating the   The authors declare that they have no competing interests.
            potential beneficial impact of UHC in mitigating the adverse
            consequences of rising unemployment on cancer mortality.  Author contributions
              This study recognizes several inherent limitations in   Conceptualization: All authors
            its analytical methodology. Firstly, the reliance on data   Investigation: Maria Asensio


            Volume 2 Issue 2 (2024)                         8                        https://doi.org/10.36922/ghes.3216
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