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Global Health Economics and
                                                                                        Sustainability





                                        REVIEW ARTICLE
                                        Preparing for disease X: A look at the

                                        psychological impact of COVID-19 on frontline
                                        healthcare workers and responses to reduce

                                        their burden



                                        Jarryd S. Ludski*
                                        Department of Emergency Medicine, University of Notre Dame  Australia, School of Medicine
                                        Sydney, Sydney, New South Wales, Australia




                                        Abstract

                                        The coronavirus 2019 (COVID-19) pandemic placed enormous strain on healthcare
                                        workers (HCWs) and systems. With over 766 million cases, a high risk of workplace-
                                        acquired infection, and a constantly evolving disease trajectory, COVID-19 placed
                                        an incredible burden on frontline HCWs. Studies on previous pandemics have
                                        highlighted the presence of significant psychological distress in HCWs; yet, mental
                                        health remained a secondary consideration in many hospitals’ pandemic responses.
                                        This review explores the psychological impact of COVID-19 on frontline HCWs during
            Academic editor:            the early stages of the pandemic and describes responses implemented by health
            Mihajlo Jakovljevic M.D. Ph.D. MAE  services to reduce it. In addition, it aims to provide a structure for the implementation
            *Corresponding author:      and evaluation of future evidence-based programs that support the well-being of
            Jarryd Ludski               frontline HCWs helping to prepare for disease X. A narrative review with a systematic
            (jarryd.ludski1@my.nd.edu.au)  approach was completed using the MEDLINE, Cumulative Index to Nursing and Allied
            Citation: Ludski, J.S. (2024).   Health Literature, and Cochrane databases. Twenty publications were included in the
            Preparing for disease X: A look   study. Symptoms of psychological distress were reported in up to 70% of frontline
            at the psychological impact of   HCWs, with as many as 50% suffering depression, 62% reporting anxiety, and 45%
            COVID-19 on frontline healthcare
            workers and responses to reduce   of those who required quarantine experiencing insomnia. Mindfulness training, safe
            their burden. Global Health Econ   rest areas, mental health practitioners, and pandemic rostering are responses that
            Sustain, 2(4):2530.         were implemented across health services during the pandemic. While the impact
            https://doi.org/10.36922/ghes.2530
                                        of COVID-19 has been enormous, its final toll remains unknown. High rates of
            Received: December 26, 2023  psychological distress among frontline HCWs mean that the impact will extend far
            Accepted: May 20, 2024      beyond the virus itself. Health services must implement evidence-based resilience
                                        strategies to ensure the safety of their frontline staff now and in the future.
            Published Online: September 26,
            2024
            Copyright: © 2024 Author(s).   Keywords: Coronavirus 2019; Frontline healthcare workers; Psychological impact;
            This is an Open-Access article   Psychological distress; Responses; Disease X
            distributed under the terms of the
            Creative Commons Attribution
            License, permitting distribution,
            and reproduction in any medium,
            provided the original work is   1. Introduction
            properly cited.
            Publisher’s Note: AccScience   In late 2019, the novel coronavirus (COVID-19) was first recognized, and on January 30,
            Publishing remains neutral with   2020, it was declared a public health emergency of international concern by the World
            regard to jurisdictional claims in
            published maps and institutional   Health Organization (WHO, 2020). Ten months later, on October 27, 2020, global

            affiliations.               case numbers exceeded 43 million, with over 1.1 million deaths (BBC, 2020) including

            Volume 2 Issue 4 (2024)                         1                        https://doi.org/10.36922/ghes.2530
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