Page 46 - GPD-1-2

Gene & Protein in Disease RUNX1 gene in female-related cancers

identification of novel prognostic and predictive signatures. https://doi.org/10.1002/ijc.29210
PLoS One, 6: e28403.
125. Jemal A, Bray F, Center MM, et al., 2011, Global cancer
https://doi.org/10.1371/journal.pone.0028403 statistics. CA Cancer J Clin. 61(2): 69–90.
115. Hnisz D, Abraham BJ, Lee TI, et al., 2013, Super‐enhancers https://doi.org/10.3322/caac.20107
in the control of cell identity and disease. Cell, 155: 934–947.
126. WCRF International. 2021, Ovarian Cancer Statistics. World
https://doi.org/10.1016/j.cell.2013.09.053 Cancer Research Fund International. Available from: https://
www.wcrf.org/dietandcancer/ovarian-cancer-statistics [Last
116. Browne G, Taipaleenmaki H, Bishop NM, et al., 2015, RUNX1
is associated with breast cancer progression in MMTV‐ accessed on 2021 Oct 25].
PyMT transgenic mice and its depletion in vitro inhibits 127. Mills K, Fuh K, 2017, Recent advances in understanding,
migration and invasion. J Cell Physiol, 230: 2522–2532. diagnosing, and treating ovarian cancer. F1000Research, 6: 84.
https://doi.org/10.1002/jcp.24989 https://doi.org/10.12688/f1000research.9977.1
117. Kadota M, Yang HH, Gomez B, et al., 2010, Delineating 128. Vogelstein B, Papadopoulos N, Velculescu VE, et al., 2013,
genetic alterations for tumor progression in the MCF10A Cancer genome landscapes. Science, 339(6127): 1546–1558.
series of breast cancer cell lines. PLoS One, 5: e9201.
https://doi.org/10.1126/science.1235122
https://doi.org/10.1371/journal.pone.0009201
129. Yu H, Pardoll D, Jove R, et al., 2009, STATs in cancer
118. Bokhman JV, 1983, Two pathogenetic types of endometrial inflammation and immunity: A leading role for STAT3. Nat
carcinoma. Gynecol Oncol, 15: 10–17. Rev Cancer, 9(11): 798–809.
https://doi.org/10.1016/0090-8258(83)90111-7 https://doi.org/10.1038/nrc2734
119. Planaguma J, Abal M, Gil‐Moreno A, et al., 2005, Up‐ 130. Monge M, Colas E, Doll A, et al., 2007, ERM/ETV5
regulation of ERM/ETV5 correlates with the degree of up-regulation plays a role during myometrial infiltration
myometrial infiltration in endometrioid endometrial through matrix metalloproteinase-2 activation in
carcinoma. J Pathol, 207: 422–429. endometrial cancer. Cancer Res, 67(14): 6753–6759.
https://doi.org/10.1002/path.1853. https://doi.org/10.1158/0008-5472.CAN-06-4487
120. Planaguma J, Liljestrom M, Alameda F, et al., 2011, Matrix 131. Aylward J, 2021, Global Burden of Cervical Cancer-together
metalloproteinase‐2 and matrix metalloproteinase‐9 for Health TogetHER for Health. Available from: https://
codistribute with transcription factors RUNX1/AML1 and togetherforhealth.org/global-burden-cervical-cancer [Last
ETV5/ERM at the invasive front of endometrial and ovarian accesed on 2021 Oct 25].
carcinoma. Hum Pathol, 42: 57–67.
132. SEER, 2022, Cancer of the Cervix Uteri Cancer Stat Facts.
https://doi.org/10.1016/j.humpath.2010.01.025 Available from: https://seer.cancer.gov/statfacts/html/
cervix.html [Last accessed on 2022 Sep 22].
121. Atienza JM, Roth RB, Rosette C, et al., 2005, Suppression of
RAD21 gene expression decreases cell growth and enhances 133. Laronda MM, Unno K, Ishi K, et al., 2013, Diethylstilbestrol
cytotoxicity of etoposide and bleomycin in human breast induces vaginal adenosis by disrupting SMAD/RUNX1-
cancer cells. Mol Cancer Ther 4: 361–368. mediated cell fate decision in the Müllerian duct epithelium.
Dev Biol, 381: 5–16.
https://doi.org/10.1158/1535-7163.MCT-04-0241
https://doi.org/10.1016/j.ydbio.2013.06.024
122. Rhodes DR, Yu J, Shanker K, et al., 2004, Large‐scale meta‐
analysis of cancer microarray data identifies common 134. Terakawa J, Rocchi A, Serna VA, et al., 2016, FGFR2IIIb-
transcriptional profiles of neoplastic transformation and MAPK activity is required for epithelial cell fate decision in
progression. Proc Natl Acad Sci U S A 101: 9309–9314. the lower Müllerian duct. Mol Endocrinol, 30: 783–795.
https://doi.org/10.1073/pnas.0401994101 https://doi.org/10.1210/me.2016-1027
123. Alonso‐Alconada L, Muinelo‐Romay L, Madissoo K, et al., 135. Robboy SJ, Young RH, Welch WR, et al., 1984, Atypical
2014, Molecular profiling of circulating tumor cells links vaginal adenosis and cervical ectropion. Association with
plasticity to the metastatic process in endometrial cancer. clear cell adenocarcinoma in diethylstilbestrol-exposed
Mol Cancer, 13: 223. offspring. Cancer, 54: 869–875.
https://doi.org/10.1186/1476-4598-13-223 https://doi.org/10.1002/1097-0142(19840901)54:5<869:aid-
cncr2820540519>3.0.co;2-i
124. Ferlay J, Soerjomataram I, Dikshit R, et al., 2015, Cancer
incidence and mortality worldwide: Sources, methods and 136. Cerami E, Gao J, Dogrusoz U, et al., 2012, The cBio
major patterns in GLOBOCAN 2012. Int J Cancer, 136(5): cancer genomics portal: An open platform for exploring
E359–E386. multidimensional cancer genomics data. Cancer Discov,

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