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Gene & Protein in Disease                                       BCL11A targets and chromatin binding patterns



               E2-2 is an essential and specific regulator of plasmacytoid   (Basel). 2022;14(14):3375.
               dendritic cell development. Cell. 2008;135(1):37-48.
                                                                  doi: 10.3390/cancers14143375
               doi: 10.1016/j.cell.2008.09.016
                                                               33.  Axelrod H, Pienta KJ. Axl as a mediator of cellular growth
            28.  Karrich JJ, Balzarolo M, Schmidlin H, et al. The transcription   and survival. Oncotarget. 2014;5(19):8818-8852.
               factor Spi-B regulates human plasmacytoid dendritic cell
               survival through direct induction of the antiapoptotic gene      doi: 10.18632/oncotarget.2422
               BCL2-A1. Blood. 2012;119(22):5191-5200.         34.  Ghosh HS, Cisse B, Bunin A, Lewis KL, Reizis B. Continuous
               doi: 10.1182/blood-2011-07-370239                  expression  of  the  transcription  factor  e2-2  maintains  the
                                                                  cell fate of mature plasmacytoid dendritic cells. Immunity.
            29.  Ceribelli M, Hou ZE, Kelly PN, et al. A druggable TCF4- and   2010;33(6):905-916.
               BRD4-dependent  transcriptional  network  sustains
               malignancy in blastic plasmacytoid dendritic cell neoplasm.      doi: 10.1016/j.immuni.2010.11.023
               Cancer Cell. 2016;30(5):764-778.                35.  García-Aznar JM, Alvarez SA, Del Castillo TB. Pivotal role of
               doi: 10.1016/j.ccell.2016.10.002                   BCL11B in the immune, hematopoietic and nervous systems:
                                                                  A  review of the BCL11A-associated phenotypes from the
            30.  Kamikubo  Y.  Genetic  compensation  of  RUNX    genetic perspective. Genes Immun. 2024;25:232-241.
               family  transcription  factors  in  leukemia.  Cancer Sci.
               2018;109(8):2358-2363.                             doi: 10.1038/s41435-024-00263-w
               doi: 10.1111/cas.13664                          36.  Engelsen AST, Lotsberg ML, Abou Khouzam R,  et al.
                                                                  Dissecting the role of AXL in cancer immune escape and
            31.  Caulier AL, Sankaran VG. Molecular and cellular   resistance to immune checkpoint inhibition. Front Immunol.
               mechanisms  that  regulate  human  erythropoiesis.  Blood.   2022;13:869676.
               2022;139(16):2450-2459.
                                                                  doi: 10.3389/fimmu.2022.869676
               doi: 10.1182/blood.2021011044
                                                               37.  Schmid ET, Pang IK, Carrera Silva EA, et al. AXL receptor
            32.  Wang W, Xu J, Khoury JD,  et al. Immunophenotypic
               and molecular features of acute myeloid leukemia with   tyrosine kinase is required for T cell priming and antiviral
               plasmacytoid dendritic cell differentiation are distinct   immunity. Elife. 2016;5:e12414.
               from blastic plasmacytoid dendritic cell neoplasm. Cancers      doi: 10.7554/eLife.12414








































            Volume 4 Issue 2 (2025)                         7                               doi: 10.36922/gpd.8131
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