Page 60 - GPD-4-2
P. 60

Gene & Protein in Disease                                                          Orexin in depression



               but not female rats. Front Behav Neurosci. 2014;8:244.  receptors and control of transmitter release.  Nat Rev
               doi: 10.3389/fnbeh.2014.00244                      Neurosci. 2004;5(2):135-145.
            148. Kim TK, Kim JE, Park JY, et al. Antidepressant effects of      doi: 10.1038/nrn1297
               exercise are produced via suppression of hypocretin/orexin   152. Zhu S, Sridhar A, Teng J, Howard RJ, Lindahl E, Hibbs
               and melanin-concentrating hormone in the basolateral   RE.  Structural and  dynamic  mechanisms  of GABA(A)
               amygdala. Neurobiol Dis. 2015;79:59-69.            receptor modulators with opposing activities. Nat Commun.
               doi: 10.1016/j.nbd.2015.04.004                     2022;13(1):4582.
            149. Tesmer AL, Li X, Bracey E, et al. Orexin neurons mediate      doi: 10.1038/s41467-022-32212-4
               temptation-resistant  voluntary  exercise.  Nat Neurosci.   153. Farrant M, Nusser Z. Variations on an inhibitory theme:
               2024;27(9):1774-1782.                              Phasic and tonic activation of GABA(A) receptors. Nat Rev
               doi: 10.1038/s41593-024-01696-2                    Neurosci. 2005;6(3):215-229.
            150. Chieffi S, Messina G, Villano I, et al. Exercise influence on      doi: 10.1038/nrn1625
               hippocampal  function:  Possible  involvement  of  orexin-A.   154. Olsen RW, Sieghart W. GABA A receptors: Subtypes provide
               Front Physiol. 2017;8:85.                          diversity of function and pharmacology. Neuropharmacology.
               doi: 10.3389/fphys.2017.00085                      2009;56(1):141-148.
            151. Engelman HS, MacDermott AB. Presynaptic ionotropic      doi: 10.1016/j.neuropharm.2008.07.045






















































            Volume 4 Issue 2 (2025)                         24                              doi: 10.36922/gpd.4210
   55   56   57   58   59   60   61   62   63   64   65