Page 50 - GPD-4-3
P. 50

Gene & Protein in Disease                                                       NLRP3 in SCI and CHM



               2018;96(6):969-977.                                doi: 10.1016/j.jare.2020.08.004
               doi: 10.1002/jnr.24114                          44.  Lin  S,  Mei  X.  Role  of  NLRP3 inflammasomes  in
                                                                  neuroinflammation diseases. Eur Neurol. 2021;83(6):576-580.
            33.  Zhong Z, Sanchez-Lopez E, Karin M. Autophagy, NLRP3
               inflammasome and auto-inflammatory/immune diseases.      doi: 10.1159/000509798
               Clin Exp Rheumatol. 2016;34(4 Suppl 98):12-16.
                                                               45.  Ravindran R, Loebbermann J, Nakaya HI, et al. The amino
            34.  Mortezaee  K,  Khanlarkhani  N,  Beyer  C,  Zendedel  AJ.   acid sensor GCN2 controls gut inflammation by inhibiting
               Inflammasome: Its role in traumatic brain and spinal cord   inflammasome activation. Nature. 2016;531(7595):523-527.
               injury. J Cell Physiol. 2018;233(7):5160-5169.
                                                                  doi: 10.1038/nature17186
               doi: 10.1002/jcp.26287
                                                               46.  Yamamoto S, Yamashina K, Ishikawa M,  et al. Protective
            35.  Curto-Reyes V, Kirschmann G, Pertin M, Drexler SK,   and therapeutic role of 2-carba-cyclic phosphatidic acid in
               Decosterd I, Suter MR. Neuropathic pain phenotype does   demyelinating. J Neuroinflammation. 2017;14:142.
               not involve the NLRP3 inflammasome and its end product      doi: 10.1186/s12974-017-0923-5
               interleukin-1β in the mice spared nerve injury model. PLoS
               One. 2015;10(7):e0133707.                       47.  Baazm M, Behrens V, Beyer C, Nikoubashman O,
                                                                  Zendedel A. Regulation of inflammasomes by application of
               doi: 10.1371/journal.pone.0133707
                                                                  omega-3 polyunsaturated fatty acids in a spinal cord injury
            36.  Ramos HJ, Lanteri MC, Blahnik G,  et al. IL-1β signaling   model. Cells. 2021;10(11):3147.
               promotes CNS-intrinsic immune control of West Nile virus      doi: 10.3390/cells10113147
               infection. PLoS Pathog. 2012;8(11):e1003039.
                                                               48.  Shiraishi Y, Kimura A, Kimura H, Ohmori T, Takahashi M,
               doi: 10.1371/journal.ppat.1003039
                                                                  Takeshita K. Deletion of inflammasome adaptor protein
            37.  Compan V, Baroja-Mazo A, López-Castejón G, et al. Cell   ASC enhances functional recovery after spinal cord injury
               volume regulation modulates NLRP3 inflammasome     in mice. J Orthop Sci. 2021;26(3):487-493.
               activation. Immunity. 2012;37(3):487-500.
                                                                  doi: 10.1016/j.jos.2020.04.006
               doi: 10.1016/j.immuni.2012.06.013
                                                               49.  Dick MS, Sborgi L, Rühl S, Hiller S, Broz P. ASC filament
            38.  Gu G, Yu H, Zou H, et al. Pyroptosis in spinal cord injury:   formation serves as a signal amplification mechanism for
               Implications for pathogenesis and therapeutic approaches.   inflammasomes. Nat Commun. 2016;7(1):11929.
               Front Biosci (Landmark Ed). 2024;29(6):210.
                                                                  doi: 10.1038/ncomms11929
               doi: 10.31083/j.fbl2906210
                                                               50.  Wu D, Zhang Y, Zhao C, et al. Disruption of C/EBPβ-Clec7a
            39.  Mangan MS, Olhava EJ, Roush WR, Seidel HM, Glick GD,   axis exacerbates neuroinflammatory injury via NLRP3
               Latz E. Targeting the NLRP3 inflammasome in inflammatory   inflammasome-mediated pyroptosis in experimental
               diseases. Nat Rev Drug Discov. 2018;17(8):588-606.  neuropathic pain. J Transl Med. 2022;20(1):583.
               doi: 10.1038/nrd.2018.97                           doi: 10.1186/s12967-022-03779-9
            40.  Seok JK, Kang HC, Cho YY, Lee HS, Lee JY. Regulation of the   51.  Rahman  SM, Janssen RC,  Choudhury  M,  et al. CCAAT/
               NLRP3 inflammasome by post-translational modifications   enhancer-binding protein β (C/EBPβ) expression regulates
               and small molecules. Front Immunol. 2021;11:618231.  dietary-induced inflammation in macrophages and adipose
                                                                  tissue in mice. J Biol Chem. 2012;287(41):34349-34360.
               doi: 10.3389/fimmu.2020.618231
                                                                  doi: 10.1074/jbc.M112.410613
            41.  Wilms H, Sievers J, Rickert U, Rostami-Yazdi M, Mrowietz U,
               Lucius  RJ.  Dimethylfumarate  inhibits  microglial  and   52.  Liu P, Cheng J, Ma S, Zhou J. Paeoniflorin attenuates
               astrocytic inflammation by suppressing the synthesis of   chronic constriction injury-induced neuropathic pain
               nitric oxide, IL-1β, TNF-α and IL-6 in an in-vitro model of   by suppressing spinal NLRP3 inflammasome activation.
               brain inflammation. J Neuroinflammation. 2010;7:30.  Inflammopharmacology. 2020;28:1495-1508.
               doi: 10.1186/1742-2094-7-30                        doi: 10.1007/s10787-020-00737-z
            42.  Guo R, Gao S, Feng Y, Mao C, Sheng W. Ulinastatin   53.  Wang YH, Tang YR, Gao X, et al. The anti-inflammatory and
               attenuates spinal cord injury by targeting AMPK/NLRP3   analgesic effects of intraperitoneal melatonin after spinal
               signaling pathway. J Chem Neuroanat. 2022;125:102145.  nerve ligation are mediated by inhibition of the NF-κB/
                                                                  NLRP3 inflammasome signaling pathway.  Brain Res Bull.
               doi: 10.1016/j.jchemneu.2022.102145
                                                                  2021;169:156-166.
            43.  Al Mamun A, Wu Y, Monalisa I, et al. Role of pyroptosis
               in spinal cord injury and its therapeutic implications. J Adv      doi: 10.1016/j.brainresbull.2021.01.015
               Res. 2021;28:97-109.                            54.  Zendedel A, Johann S, Mehrabi S,  et al. Activation and


            Volume 4 Issue 3 (2025)                         8                               doi: 10.36922/gpd.4827
   45   46   47   48   49   50   51   52   53   54   55