Page 44 - GTM-3-4

Global Translational Medicine Traumatic memories in PTSD

doi: 10.1016/j.stem.2019.09.009 doi: 10.1016/j.obmed.2020.100281
9. Zhang Y, Chen K, Sloan SA, et al. An RNA-sequencing 20. Anerillas C, Herman AB, Munk R, et al. A BDNF-TrkB
transcriptome and splicing database of glia, neurons, autocrine loop enhances senescent cell viability. Nat
and vascular cells of the cerebral cortex. J Neurosci. Commun. 2022;13(1):6228.
2014;34:11929-11947.
doi: 10.1038/s41467-022-33709-8. Erratum in: Nat Commun.
doi: 10.1523/jneurosci.1860-14.2014 2022;13(1):7540.
10. Wu Y, Hu H, Liu W, et al. Hippocampal lactate-infusion 21. Farkas CB, Dudás G, Babinszky GC, Földi L. Analysis of
enhances spatial memory correlated with monocarboxylate the virus SARS-CoV-2 as a potential bioweapon in light of
transporter 2 and lactylation. Brain Sci. 2024;14:327. international literature. Mil Med. 2023;188(3-4):531-540.
doi: 10.3390/brainsci14040327 doi: 10.1093/milmed/usac123
11. Kozlakidis Z, Shi P, Abarbanel G, Klein C, Sfera A. Recent 22. Thomas, G. Furin at the cutting edge: From protein traffic
developments in protein lactylation in PTSD and CVD: to embryogenesis and disease. Nat Rev Mol Cell Biol.
Novel strategies and targets. BioTech (Basel). 2023;12(2):38. 2002;3:753-766.
doi: 10.3390/biotech12020038 doi: 10.1038/nrm934
12. Quick S, Moss J, Rajani RM, Williams A. A vessel for change: 23. Braun E, Sauter D. Furin-mediated protein processing in
Endothelial dysfunction in cerebral small vessel disease. infectious diseases and cancer. Clin Transl Immunology.
Trends Neurosci. 2021;44(4):289-305. 2019;8(8):e1073.
doi: 10.1016/j.tins.2020.11.003 doi: 10.1002/cti2.1073
13. Yousefzadeh MJ, Zhao J, Bukata C, et al. Tissue specificity 24. Chourpiliadis C, Zeng Y, Lovik A, et al. Metabolic profile
of senescent cell accumulation during physiologic and and long-term risk of depression, anxiety, and stress-related
accelerated aging of mice. Aging Cell. 2020;19:e13094. disorders. JAMA Netw Open. 2024;7(4):e244525.

doi: 10.1111/acel.13094 doi: 10.1001/jamanetworkopen.2024.4525
14. Lehmann ML, Poffenberger CN, Elkahloun AG, 25. Mojtabavi H, Saghazadeh A, van den Heuvel L,
Herkenham M. Analysis of cerebrovascular dysfunction Bucker J, Rezaei N. Peripheral blood levels of brain-derived
caused by chronic social defeat in mice. Brain Behav Immun. neurotrophic factor in patients with post-traumatic stress
2020;88:735-747. disorder (PTSD): A systematic review and meta-analysis.
PLoS One. 2020;15(11):e0241928.
doi: 10.1016/j.bbi.2020.05.030
doi: 10.1371/journal.pone.0241928
15. Beristianos MH, Yaffe K, Cohen B, Byers AL. PTSD and risk
of incident cardiovascular disease in aging veterans. Am J 26. Sfera A, Osorio C, Rahman L, et al. PTSD as an endothelial
Geriatr Psychiatry. 2016;24(3):192-200. disease: Insights from COVID-19. Front Cell Neurosci.
2021;15:770387.
doi: 10.1016/j.jagp.2014.12.003
doi: 10.3389/fncel.2021.770387
16. Rentschler C. From danger to trauma. In: Frosh P, Pinchevski A,
editors. Media Witnessing. London: Palgrave Macmillan; 2009. 27. Wu GWY, Wolkowitz OM, Reus VI, et al. Serum brain-
derived neurotrophic factor remains elevated after long term
doi: 10.1057/9780230235762_8
follow-up of combat veterans with chronic post-traumatic
17. Zhao Y, Gao X, Bai X, Yao S, Chang YZ, Gao G. The emerging stress disorder. Psychoneuroendocrinology. 2021;134:105360.
role of furin in neurodegenerative and neuropsychiatric
diseases. Transl Neurodegener. 2022;11(1):39. doi: 10.1016/j.psyneuen.2021.105360
28. Cho S, Ying F, Sweeney G. Sterile inflammation and the
doi: 10.1186/s40035-022-00313-1
NLRP3 inflammasome in cardiometabolic disease. Biomed
18. Yang X, Yang W, McVey DG, et al. FURIN expression J. 2023;46(5):100624.
in vascular endothelial cells is modulated by a coronary
artery disease-associated genetic variant and influences doi: 10.1016/j.bj.2023.100624
monocyte transendothelial migration. J Am Heart Assoc. 29. Perl O, Duek O, Kulkarni KR, et al. Neural patterns
2020;9(4):e014333. differentiate traumatic from sad autobiographical memories
in PTSD. Nat Neurosci. 2023;26(12):2226-2236.
doi: 10.1161/JAHA.119.014333
doi: 10.1038/s41593-023-01483-5
19. AbdelMassih AF, Ye J, Kamel A, et al. A multicenter
consensus: A role of furin in the endothelial tropism 30. Iyadurai L, Visser RM, Lau-Zhu A, Porcheret K,
in obese patients with COVID-19 infection. Obes Med. Horsch A, Holmes EA, James EL. Intrusive memories of
2020;19:100281. trauma: A target for research bridging cognitive science and

Volume 3 Issue 4 (2024) 10 doi: 10.36922/gtm.3974