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Global Translational Medicine Phytonanotherapy in cancer and diabetes care

therapeutic effectiveness while minimizing negative effects. Author contributions
Additional study on NP-based drug delivery systems will
lead to more efficient and precise targeting of malignant Conceptualization: Faheem Patwekar
cells or specific diabetic areas. These advancements may Investigation: Faheem Patwekar, Mohsina Patwekar
result in improved therapeutic efficacy and less systemic Writing – original draft: Faheem Patwekar, Mohsina
toxicity. As NPs and biosensors evolve, they will provide Patwekar
more sensitive and specialized diagnostic instruments. Writing – review & editing: All authors
Early cancer and diabetes identification, as well as real- Ethics approval and consent to participate
time monitoring of therapy responses, will become more
practical. By combining CAM concepts with NP-based Not applicable.
therapies, innovative combination treatments may be
developed. These medicines may combine the benefits Consent for publication
of traditional therapy with cutting-edge nanomedicine, Not applicable.
allowing for more holistic approaches to cancer and
diabetes control. 96 Availability of data

As research advances and the safety and efficacy Not applicable.
of these therapies are confirmed, regulatory agencies
may approve and regulate CAM-based NP medicines, References
giving patients access to alternative and complementary 1. Fuad NF, Ching SM, Dzulkarnain DH, Cheong AT,
treatments in addition to traditional choices. Future Zakaria ZA. Complementary alternative medicine use
health care may priorities patient-centered care, among postpartum mothers in a primary care setting:
delivering a range of treatment options that match with A cross-sectional study in Malaysia. BMC Complement Med
individual ideas and values, with a focus on patient Ther. 2020;20:197.
preferences and overall well-being. Efforts to promote the doi: 10.1186/s12906-020-02984-7
eco-friendliness and cost-effectiveness of these therapies
may make them more accessible, especially in resource- 2. Frawley JE, McKenzie K, Janosi J, Forssman B, Sullivan E,
limited places where CAM and sustainable treatments Wiley K. The role of complementary and alternative medicine
practitioners in the information‐seeking pathway of vaccine‐
are popular. Continued developments in green synthesis hesitant parents in the Blue Mountains area, Australia.
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manufacturing, making these medicines more realistic
for wider clinical usage. Educating the general public doi: 10.1111/hsc.13361
and healthcare professionals on the benefits, risks, and 3. Upamali S, Rathnayake S. Perspectives of older people
possibilities of CAM, phytonanotherapy, and NP-based with uncontrolled type 2 diabetes mellitus towards
treatments will be critical for making informed treatment medication adherence: A qualitative study. PLoS One.
decisions. 97-101 2023;18(8):e0289834.
Overall, integrating CAM, phytonanotherapy, and NPs doi: 10.1371/journal.pone.0289834
in cancer and diabetes treatment offers great promise, 4. Kristoffersen AE, Nilsen JV, Stub T, et al. Use of
providing patients with a varied range of options and Complementary and Alternative Medicine in the context of
contributing to more effective, sustainable, and patient- cancer; prevalence, reasons for use, disclosure, information
centered health care. However, further research, rigorous received, risks and benefits reported by people with cancer
clinical trials, and regulatory backing will be required to in Norway. BMC Complement Med Ther. 2022;22(1):202.
fully realize the potential of these novel treatments. doi: 10.1186/s12906-022-03606-0

Acknowledgments 5. Vijayakumar S, Vinayagam R, Anand MA, et al. Green
synthesis of gold nanoparticle using Eclipta alba and
None. its antidiabetic activities through regulation of Bcl-2
expression in pancreatic cell line. J Drug Deliv Sci Technol.
Funding 2020;58:101786.
None. doi: 10.1016/j.jddst.2020.101786

Conflict of interest 6. Singh H, Desimone MF, Pandya S, et al. Revisiting the
green synthesis of nanoparticles: Uncovering influences of
The authors declare they have no competing interests. plant extracts as reducing agents for enhanced synthesis

Volume 4 Issue 1 (2025) 29 doi: 10.36922/gtm.5840