Page 62 - GTM-4-1
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Global Translational Medicine                                             Incretins and cardiorenal disease



            20.  Jakubowska A, Roux CW, Viljoen A. The road towards   agonist. JCI Insight. 2020;5(17):e140532.
               triple agonists: Glucagon-like peptide 1, glucose-dependent      doi: 10.1172/jci.insight.140532
               insulinotropic polypeptide and glucagon receptor-an
               update. Endocrinol Metab (Seoul). 2024;39(1):12-22.  31.  Zeitler P, Galindo RJ, Davies MJ, et al. Early-onset type 2
                                                                  diabetes and tirzepatide treatment: A post hoc analysis
               doi: 10.3803/EnM.2024.1942
                                                                  from the SURPASS clinical trial program.  Diabetes Care.
            21.  Loomba R, Hartman ML, Lawitz EJ, et al. Tirzepatide for   2024;47(6):1056-1064.
               metabolic dysfunction-associated steatohepatitis with liver      doi: 10.2337/dc23-2356
               fibrosis. N Engl J Med. 2024;391:299-310.
                                                               32.  Malhotra A, Bednarik J, Chakladar S, et al. Tirzepatide for
               doi: 10.1056/NEJMoa2401943
                                                                  the treatment of obstructive sleep apnea: Rationale, design,
            22.  Abdelmalek MF, Suzuki A, Sanchez W,  et al. A phase 2,   and sample baseline characteristics of the SURMOUNT-
               adaptive randomized, double-blind, placebo-controlled,   OSA phase 3 trial. Contemp Clin Trials. 2024;141:107516.
               multicenter,  52-week  study  of  HM15211  in  patients  with      doi: 10.1016/j.cct.2024.107516
               biopsy-confirmed  non-alcoholic  steatohepatitis-study
               design and rationale of HM-TRIA-201 study. Contemp Clin   33.  ClinicalTrials.gov Identifier: NCT04255433.  A Study  of
               Trials. 2023;130:107176.                           Tirzepatide (LY3298176) Compared with Dulaglutide on
                                                                  Major Cardiovascular Events in Participants with Type
               doi: 10.1016/j.cct.2023.107176
                                                                  2 Diabetes (SURPASS-CVOT). Available from:  https://
            23.  Nauck MA, Müller TD. Incretin hormones and type 2   clinicaltrials.gov/study/nct04255433 [Last accessed on 2024
               diabetes. Diabetologia. 2023;66(10):1780-1795.     Jun 10].
               doi: 10.1007/s00125-023-05956-x                 34.  Jastreboff AM, Kaplan LM, Frias JP, et al. Triple-hormone-
                                                                  receptor agonist retatrutide for obesity: A phase 2 trial. N
            24.  Nauck MA, Quast DR, Wefers J, Meier JJ. GLP-1 receptor
               agonists in the treatment of type 2 diabetes-state-of-the-art.   Engl J Med. 2023;389:514-526.
               Mol Metab. 2021;46:101102.                         doi: 10.1056/NEJMoa2301972
               doi: 10.1016/j.molmet.2020.101102               35.  Rosenstock J, Frias J, Jastreboff AM, et al. Retatrutide, a GIP,
                                                                  GLP-1 and glucagon receptor agonist, for people with type
            25.  Tschöp M, Nogueiras R, Ahrén B. Gut hormone-
               based pharmacology: Novel formulations and future   2 diabetes: A randomised, double-blind, placebo and active-
               possibilities for metabolic disease therapy.  Diabetologia.   controlled, parallel-group, phase 2 trial conducted in the
               2023;66(10):1796-1808.                             USA. Lancet. 2023;402(10401):529-544.
                                                                  doi: 10.1016/S0140-6736(23)01053-X
               doi: 10.1007/s00125-023-05929-0
                                                               36.  Jensen TL, Brønden A, Karstoft K, Sonne DP,
            26.  Mann JFE, Rossing P, Bakris G, et al. Effects of semaglutide
               with and without concomitant SGLT2 inhibitor use in   Christensen MB. The body weight reducing effects of
               participants with type 2 diabetes and chronic kidney disease   tirzepatide in people with and without type 2 diabetes:
               in the flow trial. Nat Med. 2024;30:2849-2856.     A review on efficacy and adverse effects.  Patient Prefer
                                                                  Adherence. 2024;18:373-382.
               doi: 10.1038/s41591-024-03133-0
                                                                  doi: 10.2147/PPA.S419304
            27.  Moiz A, Levett JY, Filion KB, Peri K, Reynier P, Eisenberg MJ.
               Long-term efficacy and safety of once-weekly semaglutide   37.  Melson E, Ashraf U, Papamargaritis D, Davies MJ. What is
               for weight loss in patients without diabetes: A systematic   the pipeline for future medications for obesity? Int J Obes
               review and meta-analysis of randomized controlled trials.   (Lond). 2024.
               Am J Cardiol. 2024;222:121-130.                    doi:10.1038/s41366-024-01473-y
               doi: 10.1016/j.amjcard.2024.04.041              38.  Locatelli JC, Costa JG, Haynes A,  et al. Incretin-based
                                                                  weight loss pharmacotherapy: Can resistance exercise
            28.  Teva Launches Generic Formulation of Liraglutide in US.
               Available from:  https://www.pharmacytimes.com/view/  optimize  changes in  body  composition?  Diabetes Care.
               teva-launches-generic-formulation-of-liraglutide-in-us   2024:dci230100.
               [Last accessed on 2024 Jun 28].                    doi: 10.2337/dci23-0100
            29.  Scheen AJ. Dual GIP/GLP-1 receptor agonists: New   39.  Conte C, Hall KD, Klein S. Is weight loss-induced muscle
               advances for treating type-2 diabetes.  Ann Endocrinol   mass loss clinically relevant? JAMA. 2024;332(1):9-10.
               (Paris). 2023;84(2):316-321.
                                                                  doi: 10.1001/jama.2024.6586
               doi: 10.1016/j.ando.2022.12.423
                                                               40.  Pillai P, Modarressi T.  GLP1RAs in Clinical Practice:
            30.  Willard FS,  Douros  JD,  Gabe  MB,  et al.  Tirzepatide is   Therapeutic Advances and Safety Perspectives; 2024. American
               an imbalanced and biased dual GIP and GLP-1 receptor   College of Cardiology. Available from: https://www.acc.org/


            Volume 4 Issue 1 (2025)                         54                              doi: 10.36922/gtm.4405
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