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Global Translational Medicine





                                        PERSPECTIVE ARTICLE
                                        YeeZzzy does it: Using Kanye West’s tweets

                                        to identify sleep and emotional disturbances
                                        through digital rest-activity rhythms analysis



                                        Matthew J. Reid * , Darlynn M. Rojo-Wissar 2,3  , Michelle Mei , Moira Differding ,
                                                                                            1
                                                                                                            4
                                                     1
                                        Michael T. Smith 1  , and Michael G. Smith 5
                                        1 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine,
                                        Baltimore, MD, United States of America
                                        2 Department of Psychiatry and Human Behavior,  Alpert Medical School of Brown University,
                                        Providence, Rhode Island, United States of America
                                        3 Bradley/Hasbro Children’s Research Center, E.P. Bradley Hospital, East Providence, Rhode Island,
                                        United States of America
                                        4 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore,
                                        Maryland, United States of America
                                        5 Department of Occupational and Environmental Medicine, School of Public Health and Community
                                        Medicine, University of Gothenburg, Gothenburg, Västra Götaland, Sweeden



                                        Abstract

                                        One of the greatest challenges faced by precision medicine is the identification of
            *Corresponding author:      biomarkers capable of detecting clinically meaningful change at the individual level,
            Matthew J. Reid             not just among large-scale population studies. To this end, the high-volume nature
            (mreid27@jhmi.edu)
                                        of an individual’s social media data could be leveraged with single-user precision to
            Citation: Reid MJ, Rojo-Wissar DM,   monitor sleep patterns and tweet content to determine emotional state. However,
            Mei M, Differding M, Smith MT,
            Smith MG. YeeZzzy does it: Using   there  is  a  lack  of  established  methods  to  detect  and  estimate  sleep  and  mood
            Kanye West’s tweets to identify   using social-media activity. We present here a new approach (digital rest-activity
            sleep and emotional disturbances   rhythms analysis) to using social media to track both sleep and mood, with potential
            through digital rest-activity rhythms
            analysis. Global Transl Med.   applications to mental health monitoring and prevention. Our proof-of-concept
            2025;4(2):51-57.            showed that the emotional content of a single user’s tweets (Kanye West “@Ye”)
            doi: 10.36922/gtm.5176      were influenced by sleep disturbances inferred from usage over a 2-year period. We
            Received: October 17, 2024  herein provide an ethical and theoretical-framework of how to proceed among this
            Revised: December 7, 2024   sensitive yet potentially fruitful field.
            Accepted: December 13, 2024
            Published online: January 9, 2025  Keywords: Sleep; Twitter; Social media; Depression; Emotion; Mood
            Copyright: © 2025 Author(s).
            This is an Open-Access article
            distributed under the terms of the
            Creative Commons Attribution   1. Introduction
            License, permitting distribution,
            and reproduction in any medium,   One of the greatest challenges faced by the field of precision medicine is the identification
            provided the original work is   of biomarkers capable of detecting clinically meaningful change at the individual level,
            properly cited.             not just among large-scale population studies. To this end, the evermore present social
            Publisher’s Note: AccScience   mediaverse provides unparalleled access to ecologically valid databases of digital
            Publishing remains neutral with   biomarkers that could be leveraged with single-user precision to support mental health
            regard to jurisdictional claims in                                                    1
            published maps and institutional   care by monitoring use patterns and emotional state. An illustrative study  published in
            affiliations.               Science demonstrated the presence of circadian rhythmicity in the emotional content


            Volume 4 Issue 2 (2025)                         51                              doi: 10.36922/gtm.5176
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