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Global Translational Medicine                                             Mass balance vs. energy balance



            Dr.  Arencibia-Albite’s foundational work highlights the   2.   Theodorakis N. Comment to the manuscript “chronic
            potential for collaborative exploration to deepen our   positive mass balance is the actual etiology of
            understanding of body weight regulation – an endeavor I   obesity: A  living review”.  Glob  Transl Med. 2025;4:
            hope will inspire further research and refinement.    142-143.
                                                                  doi: 10.36922/gtm.8079
            Conflict of interest
                                                               3.   Arencibia-Albite F. Serious analytical inconsistencies
            The author declares no conflict of interest.          challenge the validity of the energy balance theory. Heliyon.
            References                                            2020;6:e04204.
                                                                  doi: 10.1016/j.heliyon.2020.e04204
            1.   Manninen AH. Chronic positive mass balance is the
               actual etiology of obesity: A living review. Glob Transl Med.   4.   Arencibia-Albite  F.  The  energy  balance  theory  is  an
               2023;2(1):222.                                     inconsistent paradigm. J Theor Biol. 2022;550:111240.
               doi: 10.36922/gtm.222                              doi: 10.1016/j.jtbi.2022





























































            Volume 4 Issue 3 (2025)                        120                          doi: 10.36922/GTM025120029
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