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Global Translational Medicine Mass balance vs. energy balance
Dr. Arencibia-Albite’s foundational work highlights the 2. Theodorakis N. Comment to the manuscript “chronic
potential for collaborative exploration to deepen our positive mass balance is the actual etiology of
understanding of body weight regulation – an endeavor I obesity: A living review”. Glob Transl Med. 2025;4:
hope will inspire further research and refinement. 142-143.
doi: 10.36922/gtm.8079
Conflict of interest
3. Arencibia-Albite F. Serious analytical inconsistencies
The author declares no conflict of interest. challenge the validity of the energy balance theory. Heliyon.
References 2020;6:e04204.
doi: 10.1016/j.heliyon.2020.e04204
1. Manninen AH. Chronic positive mass balance is the
actual etiology of obesity: A living review. Glob Transl Med. 4. Arencibia-Albite F. The energy balance theory is an
2023;2(1):222. inconsistent paradigm. J Theor Biol. 2022;550:111240.
doi: 10.36922/gtm.222 doi: 10.1016/j.jtbi.2022
Volume 4 Issue 3 (2025) 120 doi: 10.36922/GTM025120029

