Page 529 - IJB-10-4

International Journal of Bioprinting 3D printed substrate for adhesion tests

Figure 2. Comparison of peak adhesive forces generated from human skin, 3D-printed polypropylene probes, and stainless steel probes. (a) No significant
difference in peak adhesive force between PP probes and the skin adhered to SS probes. (b) Significant reduction in peak adhesive force required to unbind
skin and PP probe as compared to industrial standard TA-57R SS probe. Results are expressed as mean ± standard deviation (n = 5). ****p < 0.0001.

test data were observed when human skin adhered to coat weights of PSA-4302 and PSA-4501 on glass (i.e., non-
the SS probe (relative standard deviation [RSD]: 48.04%) elongated surface). Moreover, no significant difference was
compared to PP probes (RSD: 1.95%). Results also observed in peak adhesive forces at 15 and 10 mg/cm
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demonstrated a significant increase (p < 0.0001) in peak coat weights of PSAs on glass. For 3D-printed PP probes,
adhesive force required to unbind the SS probe compared there was no significant difference at 5 and 10 mg/cm coat
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to the PP probe and human skin (Figure 2). weights of PSA-4302 and PSA-4501 on glass (Figure 5).
3.3. Effect of coat weight on the 3D probe/plate 3.5. Effect of backing membrane elongation on the
Tack test results for SS probes demonstrated that PSA- adhesion properties of pressure-sensitive adhesives
4302 significantly increased (p < 0.05) the peak adhesive In this study, amine-compatible PSA-4302 and non-amine-
force at 10 mg/cm compared to 5 mg/cm coat weight. compatible PSA-4501 were selected to evaluate the effect of
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However, PSA-4501 did not exhibit a significant difference backing membranes on the adhesion properties of PSAs.
in both 5 and 10 mg/cm coat weights. In contrast, tack
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results for PP probes displayed a significant increase (p < 3.5.1. Probe tack test using stainless steel probes
0.001) in peak adhesive force at 10 mg/cm compared to The SS probe did not exhibit any significant difference
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5 mg/cm coat weight for both PSA-4302 and PSA-4501 in tack properties for PSA-4302 at 5, 10, and 15 mg/cm
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(Figure 3). Peel adhesion data for SS plates indicated a coat weights on backing membranes 9733, 9723, and 9735,
significant increase in peel adhesive force at 10 mg/cm respectively, with their respective elongations of 70%, 75%,
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compared to 5 mg/cm coat weight for PSA-4302 laminates. and 100%. However, a significant increase in peak adhesive
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Similarly, PP plate data also displayed a significant increase force was observed for PSA-4302 at 10 and 15 mg/cm coat
in the peel adhesion force at 10 mg/cm compared to 5 mg/ weights in all backing membranes (9733, 9723, and 9735)
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cm coat weight for PSA-4302 laminates (Figure 4). compared to the glass surface. Non-amine-compatible
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PSA-4501 also displayed a significant increase in peak
3.4. Effect of coat weight on the adhesion adhesive force at 5, 10, and 15 mg/cm coat weights in all
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properties of pressure-sensitive adhesives on backing membranes 9733, 9723, and 9735 compared to
non-elongated surfaces the glass surface. Similar to PSA-4302, PSA-4501 did not
For SS probes, there was a significant increase (p < 0.05) in display any significant difference in tack properties at 5,
peak adhesive force at 10 mg/cm compared to 5 mg/cm 2 10, and 15 mg/cm coat weights in all backing membranes
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Volume 10 Issue 4 (2024) 521 doi: 10.36922/ijb.3735