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International Journal of Bioprinting Collagen hydrolysate-loaded ODMA/PEGDMA scaffold

Figure 17. Live/dead fluorescence staining images of chondrocytes on scaffolds with different compositions over 72 h at 5× magnification. Abbreviations:
CH, collagen hydrolysate; ODMA, oligomers of dopamine methacrylate; PEGDMA, polyethylene glycol dimethacrylate. Scale bars: 200 µm.
combining these components will enhance their accommodate cells, growth factors, or drugs within. In
mechanical properties and cell encapsulation capabilities, addition, the scaffold can be precisely replicated using DLP
making it feasible to create hybrid scaffolds with durable bioprinting techniques.
parts to withstand applied forces and weaker parts
that can serve as hydrogels to encapsulate cells, growth 4. Conclusion
factors, or drugs within the material. This facilitates the We successfully synthesized DMA and verified its
growth and differentiation of chondrocyte cells, allowing chemical structure and composition using NMR and
for faster cartilage regeneration compared to scaffolds FTIR, respectively. These analyses confirmed that
made from conventional thermoplastic materials, such the structure of DMA aligned with previous studies.
as polycaprolactone (PCL), poly(glycolic acid) (PGA), Additionally, DSC analysis of DMA’s thermal properties
or polylactide (PLA), which cannot form hydrogels and identified a melting point at 118°C. Further exploration

Volume 10 Issue 6 (2024) 356 doi: 10.36922/ijb.4385