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3D Printed PLA/HAp Biocomposites




                                           A                 B                  C






                                           D                 E                  F






                                           G                 H                  I






                                           J                  K                 L






           Figure  8. Digital  micrographs  of  3D  printed  polylactic  acid/hydroxyapatite  scaffolds  immersed  for  72  h  in  simulated  body  fluid  for
           biomineralization activity.

                        A                                   B






















           Figure 9. (A) Weight gain (%) and (B) X-ray diffractograms of the 3D printed polylactic acid/hydroxyapatite composites after the 72-h
           immersion test in SBF.

           creating other sites with less material leading to void   shown in Figure 9A and B, respectively. As seen on the
           formation.                                          digital micrographs, the 3D printed pure PLA (PLA/0H)
                                                               exhibited  an  etching  response  to  soaking  in  SBF. This
           3.5. In vitro biomineralization                     was supported by the mass loss in Figure 9A. Pure PLA

           A preliminary  in vitro bioactivity  test  was done by   remains to be partly hydrophilic, and hence subjecting it
           immersing the 3D printed PLA/HAp composite samples   to an aqueous immersion resulted to some PLA dissolving
           in  SBF  solutions  for  24,  48,  and  72  h,  and  the  digital   away.
           micrograph results are  shown in  Figure  8, while  the   The PLA/HAp composites reported varying weight
           percent  weight  gain  and  X-ray  diffractograms  are   gains, with the trend that was increasing. HAp particles

           120                         International Journal of Bioprinting (2021)–Volume 7, Issue 1
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