Page 127 - IJB-7-1
P. 127

RESEARCH ARTICLE

           A Novel Bespoke Hypertrophic Scar

           Treatment: Actualizing Hybrid Pressure and Silicone

           Therapies with 3D Printing and Scanning


           Lung Chow , Kit-lun Yick *, Yue Sun , Matthew S. H. Leung , Mei-ying Kwan , Sun-pui Ng ,
                      1
                                               1,2
                                                                                        1
                                                                                                     3
                                                                       1
                                    1
           Annie Yu , Joanne Yip , Ying-fan Chan 5
                                 1
                    4
           1 Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hong Kong
           2 School of Fashion Design and Engineering, Zhejiang Sci-Tech University, Hangzhou
           3 Division of Science, Engineering and Health Studies, College of Professional and Continuing Education, The Hong Kong
           Polytechnic University, Hong Kong
           4 Department of Advanced Fibro Science, Kyoto Institute of Technology, Japan
           5 Department of Occupational Therapy, Prince of Wales Hospital, Hong Kong
           Abstract: The treatment of hypertrophic scars (HSs) is considered to be the most challenging task in wound rehabilitation.
           Conventional silicone sheet therapy has a positive effect on the healing process of HSs. However, the dimensions of the silicone
           sheet are typically larger than those of the HS itself which may negatively impact the healthy skin that surrounds the HS.
           Furthermore, the debonding and displacement of the silicone sheet from the skin are critical problems that affect treatment
           compliance. Herein, we propose a bespoke HS treatment design that integrates pressure sleeve with a silicone sheet and use of
           silicone gel using a workflow of three-dimensional (3D) printing, 3D scanning and computer-aided design, and manufacturing
           software. A finite element analysis (FEA) is used to optimize the control of the pressure distribution and investigate the effects
           of the silicone elastomer. The result shows that the silicone elastomer increases the amount of exerted pressure on the HS and
           minimizes unnecessary pressure to other parts of the wrist. Based on this treatment design, a silicone elastomer that perfectly
           conforms to an HS is printed and attached onto a customized pressure sleeve. Most importantly, unlimited scar treating gel can
           be applied as the means to optimize treatment of HSs while the silicone sheet is firmly affixed and secured by the pressure sleeve.

           Keywords: Surgical scars; Hypertrophic scars; Finite element analysis; 3D-printing; 3D-scanning

           *Correspondence to: Kit-lun Yick, Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hong Kong;
           tcyick@polyu.edu.hk

           Received: November 24, 2020; Accepted: December 30, 2020; Published Online: January 25, 2021
           Citation: Chow L, Yick KL, Sun Y, et al., 2021, A Novel Bespoke Hypertrophic Scar Treatment: Actualizing Hybrid Pressure
           and Silicone Therapies with 3D Printing and Scanning. Int J Bioprint, 7(1):327. http://doi.org/10.18063/ijb.v7i1.327

           1. Introduction                                     blood loss. With aid of the coagulation factors, the plug
                                                               can be further stabilized  by platelet  aggregation  and
           Wound healing  is a complicated  process that  can   the formation of fibrin scaffold which are driven by the
           be  described  as the  restitution of natural  anatomical   enzymatic cascade [1,2] . The second phase of wound healing
           relationships  and physiological  integrity  of the  injured   is inflammation which occurs around the 5 days after the
           tissues . The wound healing process can be divided into   injury. In this phase, the immune system is triggered to
                [1]
           overlapping phases with reference to the phase of recovery,   activate the inflammatory reactions to prevent infection.
           including  hemostasis,  inflammation,  proliferation,  and   Neutrophils  and  macrophages  are  recruited  to  remove
           remodeling.  Hemostasis  occurs immediately  after  the   any invading bacteria or foreign debris . The third phase
                                                                                               [3]
           tissue or capillary blood vessels are damaged. The platelet   is the proliferation which occurs  around 5 – 10 days
           degranulation  creates  a hemostatic  plug to prevent  the   after the injury and may last for 3 – 6 weeks. The main

           © 2021 Chow, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International
           License (http://creativecommons.org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the
           original work is properly cited.
                                                                                                           123
   122   123   124   125   126   127   128   129   130   131   132