Page 130 - IJB-7-1
P. 130

Actualizing Hybrid Pressure and Silicone Therapies with 3D Printing and Scanning
              A                               F                              G











              B                               E                              H











              C                               D                               I










           Figure 1. Schematic of workflow of patient specific pressure sleeve with silicone elastomer insert. (A) 3D scanning to obtain geometry and
           texture of hand and HS. (B) 3D modeling of a silicone elastomer which fits the HS. (C) Flattening of 3D model as pattern for pressure sleeve.
           (D) 3D printing of silicone elastomer on fabric by using extrusion-based 3D printer and photo of the printed silicone on fabric. (E) Producing
           pressure sleeve by applying stitches on the patterns. (F) Developing the FEM including the pressure sleeve, bone, silicone, and hand models.
           (G) Validation of the FEM for pressure through wear trial. (H) Pressure optimization through FEA. (I) Photo of the final pressure sleeve
           with customized silicone elastomer insert.

           of the HS was first created and the thickness had to be   and the patterning of the pressure sleeve  (Figures  1C
           larger than the height of the HS. Then, the box model   and D). Before the silicone insert model was imported
           was moved to the area where the HS was submerged into   into  the  3D-printer  (3D-Bioplotter  Manufacturer
                                                                                                ®
           the box model. The boundaries of the box model were   Series), a slicing process was  done to determine  the
           adjusted to the shape of the HS boundaries based on the   number of printed layers and the path of printing for each
           scanned color of the HS and hand by moving the vertex   layer. A biocompatible silicone elastomer (SILBIONE
                                                                                                              ®
           or edges of the box model. Note that the number of length   RTV 4410 1:1 A&B) was mixed  with  0.2 and  2 wt%
           and width segments of the box model has to be adequate   of a silicone  thickener  (THI-VEXTM) and degassed
           to carry out the boundary adjustment process. Once the   respectively for the 3D printing process. The settings of
           boundaries of the silicone elastomer model fit with those   the 3D printing process and the specifications of the warp
           of the HS, a Boolean operation can be done to subdivide   knitted fabric are shown  in  Supplementary Tables  1
           the overlap volume of the silicone elastomer and hand   and 2, respectively. A multi-viscosity printing technique
           model. The modeling process is shown in Figure 1B. The   developed by our team was adopted. The silicone mixture
           created model can be saved as a stereolithography (stl)   with lower viscosity was extruded through the nozzle
           file for the 3D printing process. Once the insert model   of the 3D printer and deposited onto the warp knitted
           was created, the coordinations of the model were rotated   fabric  to improve  the  adhesion  between  the  silicone
           and adjusted to the proper position for the 3D printing of   and fabric. Apart from the first layer of printing, higher
           silicone onto fabric.                               viscosity print mixture was adopted to maintain the form
                                                               accuracy  of the  silicone  part.  The  shear force  of the
           (2) 3D printing and patterning                      sample constructed using the multi-viscosity  technique

           The third and fourth steps of the design framework are   was increased from about 10 to 60 N in comparison to
           3D printing of silicone elastomer on the pressure sleeve   normal  printing  approaches  which  should  be  sufficient

           126                         International Journal of Bioprinting (2021)–Volume 7, Issue 1
   125   126   127   128   129   130   131   132   133   134   135