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3D Printed Electronic Patch for pH and Hydration Sensing
                        A                                    B





















           Figure 5. Hysteresis plot (A) and (B) made by using mean data points of Figure S4a and S4b, respectively.





















           Figure 6. Resistance versus time plots indicating change in hydration.
           resistance depends on below equations with change in   4. Conclusions
           fluid content and surface area of electrodes in contact
           with the fluid.                                     The  work demonstrates  the  feasibility  of  fully  printing
                                                               a wound management  patch.  The wound patch  was
                                                               fabricated  with the purpose of enhancing  wound.  The
              U
           R =                                          (1)    focus is to measure the health status of the wound through
               I                                               indicative  pH and  hydration  levels  in  a  single  patch.
                                                               A PDMS-based substrate was used to print SWCNT and
                                                               silver functional inks as sensing elements. Inkjet printing
                 L
           R =  ρ                                       (2)    was employed for the patch and optimized  to get the
                 A                                             desired design and dimensions.  The fabricated  sensor
                                                               patch has a sensitivity  of 7.1  ohm/pH for wound pH

               where  R  =  eesistance  (Ω),  U  =  voltage  (V),   levels. The measured resistance changes suggested that
           I = current (A), ⍴= resistivity (Ω m), L = length between   the sensor is able to measure wound exudate and serve as
           electrodes (m), and A = surface area of electrodes (m ).  detector for wound fluids. It was also concluded that the
                                                       2
               The sensor patch was fabricated for the purpose of   sensitivity and precision of the patch can be controlled
           validating the measurements for wound management.   by removal of excess SWCNTs and through the printing
           The hydration sensor gives an indication of the     process.
           presence of fluid in the wound, and if that is true, the   Acknowledgments
           measurements of the pH sensor originate from the
           wound fluid and not the dried-out residue left on the   This work was supported by the  Dean Start-up  grant,
           pH sensor.                                          Science and Technology, Aarhus University, Denmark.


           46                          International Journal of Bioprinting (2022)–Volume 8, Issue 1
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