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PERSPECTIVE ARTICLE

           Stakeholder Perspectives on the Current and Future of

           Additive Manufacturing in Healthcare


           Victor M. Villapún , Luke N. Carter , Steven Avery , Alba González-Álvarez , James W. Andrews ,
                                              1
                                                              2
                              1
                                                                                                            4
                                                                                       3
           Sophie Cox 1
           1 School of Chemical Engineering, University of Birmingham, Edgbaston B15 2TT, United Kingdom
           2 Renishaw New Mills, Headquarters, Gloucestershire, GL12 8JR, United Kingdom
           3 Department of Bioengineering and Aerospace Engineering, University Carlos III of Madrid, 28911, Madrid, Spain
           4 School of Mathematics, University of Birmingham, Edgbaston B15 2TT, United Kingdom

           Abstract: Additive  manufacturing  (AM) technologies  have  disrupted  many  supply  chains  by  making  new  designs  and
           functionalities  possible.  The  opportunity  to  realize  complex  customized  structures  has  led  to  significant  interest  within
           healthcare; however, full utilization critically requires the alignment of the whole supply chain. To offer insights into this
           process, a survey was conducted to understand the views of different medical AM stakeholders. The results highlighted an
           agreement between academics, designers, manufacturers, and medical experts, that personalization and design control are
           the main benefits of AM. Interestingly, surface finish was consistently identified as an obstacle. Nevertheless, there was a
           degree of acceptance that post-processing was necessary to achieve appropriate quality control. Recommendations were
           made for extending the use of in situ process monitoring systems to support improved reproducibility. Variations in the future
           vision of AM were highlighted between stakeholder groups and areas of interest for development noted for each stakeholder.
           Collectively, this survey indicates that medical stakeholders agree on the capabilities of AM but have different priorities for
           its implementation and progression. This highlights a degree of disconnection among the supply chain at a ground level; thus,
           collaboration on AM specific standards and enhancement of communication between stakeholders from project inception is
           recommended.
           Keywords: Additive manufacturing; Survey; Healthcare

           *Correspondence to: S. Cox, School of Chemical Engineering, University of Birmingham, Edgbaston B15 2TT, United Kingdom;
           s.c.cox@bham.ac.uk

           Received: March 10, 2022; Accepted: May 10, 2022; Published Online: June 29, 2022
           Citation: Villapún VM, Carter LN, Avery S, et al., 2022, Stakeholder Perspectives on the Current and Future of Additive Manufacturing in
           Healthcare, Int J Bioprint. 8(3):586. http://doi.org/10.18063/ijb.v8i3.586

           1. Introduction                                     (AM) since these technologies enable the production of
                                                               complex, fully-dense and functional components directly
           By 2015 the term “The  Fourth Industrial  Revolution”   from computer-aided  design (CAD), and organically
           had  spread  past  industry-specific  conferences  and
           entered general  use . It was becoming  a catch-all   inspired and topologically optimized designs that are not
                             [1]
           phrase  encompassing  the  growing automation  in   achievable  through subtractive  machining.  Initially, a
           manufacturing, the Internet of Things, and an increased   simple prototyping technique, AM has evolved to become
           reliance on digital communication. The Fourth Industrial   one of the most potentially disrupting processes across
                                                                                                [2]
           Revolution  also relies heavily  on the preceding  three   multiple sectors, particularly healthcare .
           decades  of development  in  three-dimensional  (3D)-   The quick evolution of AM within healthcare has
           printing  to enable highly customizable,  decentralized,   led to different stages of adoption; polymer 3D printing
           and on-demand manufacturing  typically  without many   is nearing the plateau of productivity while bioprinting
           of the constraints of conventional processes. There has   continues to climb the peak of inflated expectations [3,4] .
           been  a  sustained  interest  in additive  manufacturing   During the early stages of AM adoption, polymer based
           © 2022 Author(s). This is an Open-Access article distributed under the terms of the Creative Commons Attribution License, permitting distribution and
           reproduction in any medium, provided the original work is properly cited.
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