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International Journal of Bioprinting
REVIEW ARTICLE
Research progress and challenges of
bioprinting in wound dressing and healing:
Bibliometrics-based analysis and perspectives
Shuduan Mao , Junjie Man , Jialei Wang , Li Fu *, Chengliang Yin ,
3
2
4,5
2
1
Hassan Karimi-Maleh 6,7,8
1 Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province, Interdisciplinary
Research Academy, Zhejiang Shuren University, Hangzhou 310015, P.R. China
2 Key Laboratory of Novel Materials for Sensor of Zhejiang Province, College of Materials and
Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, P.R. China
3
Shining3D Tech Co., Ltd, Hangzhou 311258, P.R. China
4 National Engineering Laboratory for Medical Big Data Application Technology, Chinese PLA
General Hospital, Beijing, P.R. China
5 Medical Big Data Research Center, Medical Innovation Research Division of PLA General Hospital,
Beijing, P.R. China
6 School of Resources and Environment, University of Electronic Science and Technology of China,
611731, Xiyuan Ave, Chengdu, P.R. China
7 Department of Chemical Engineering, Quchan University of Technology, Quchan 9477177870, Iran
8 Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, 2028,
Johannesburg 17011, South Africa
Abstract
*Corresponding author:
Li Fu (fuli@hdu.edu.cn) As the body’s largest organ, the skin has important roles in barrier function, immune
response, prevention of water loss and excretion of waste. Patients with extensive
Citation: Mao S, Man J, Wang J,
et al., 2023, Research progress and and severe skin lesions would die due to insufficient graftable skin. Commonly
challenges of bioprinting in wound used treatments include autologous skin grafts, allogeneic/allogeneic skin grafts,
dressing and healing: Bibliometrics- cytoactive factors, cell therapy, and dermal substitutes. However, traditional
based analysis and perspectives.
Int J Bioprint, 9(2): 653. treatment methods are still inadequate regarding skin repair time, treatment
http://doi.org/10.18063/ijb.v9i2.653 costs, and treatment results. In recent years, the rapid development of bioprinting
Received: June 29, 2022 technology has provided new ideas to solve the above-mentioned challenges. This
Accepted: August 19, 2022 review describes the principles of bioprinting technology and research advances
Published Online: December 22, in wound dressing and healing. This review features a data mining and statistical
2022
analysis of this topic through bibliometrics. The annual publications on this topic,
Copyright: © 2022 Author(s). participating countries, and institutions were used to understand the development
This is an Open Access article history. Keyword analysis was used to understand the focus of investigation and
distributed under the terms of the
Creative Commons Attribution challenges in this topic. According to bibliometric analysis, bioprinting in wound
License, permitting distribution and dressing and healing is in an explosive phase, and future research should focus on
reproduction in any medium, discovering new cell sources, innovative bioink development, and developing large-
provided the original work is
properly cited. scale printing technology processes.
Publisher’s Note: Whioce
Publishing remains neutral with Keywords: Bioprinting; Wound dressing; Wound healing; Tissue engineering;
regard to jurisdictional claims in
published maps and institutional Keratinocyte; Stem cell
affiliations.
Volume 9 Issue 2 (2023) 49 http://doi.org/10.18063/ijb.v9i2.653

