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26  INNOSC Theranostics and Pharmacological Sciences, 2023, Vol. 6, No. 1                    Kivrak, et al.

           in scleroderma patients. The study provides an              Vonk, M.C.; Walker, U.A.; Chung, L.; Collier, D.H.; Csuka, M.E.;
           overview of cardiovascular disease risk factors in          Fessler, B.J.; Guiducci, S.; Herrick, A.; Hsu, V.M.; Jimenez, S.;
                                                                       Kahaleh, B.; Merkel, P.A.; Sierakowski, S.; Silver, R.M.;
           scleroderma patients in the Turkish population. Our         Simms,  R.W.;  Varga,  J.;  Pope,  J.E.  2013  Classification  Criteria
           study is a pioneer for more complex studies to be           for Systemic Sclerosis: An American College of Rheumatology/
                                                                       European  League  Against  Rheumatism  Collaborative  İnitiative.
           done in the scleroderma patient group.                      Ann. Rheum. Dis., 2013, 72, 1747–55.
                                                                [5]    Semenov,  V.; Kuryata, O.; Lysunets,  T. Clinical Pattern of
           Acknowledgments                                             Systemic Sclerosis in Central Ukraine.  Association Between
                                                                       Clinical Manifestations of Systemic Sclerosis and Hypertension.
           None.                                                [6]    Reumatologia, 2018, 56(1), 24–30.
                                                                       Minier, T.; Guiducci, S.; Bellando-Randone, S.; Bruni, C.; Lepri, G.;
                                                                       Czirják,  L.;  Distler,  O.; Walker,  U.A.;  Fransen,  J.; Allanore, Y.;
           Funding                                                     Denton, C.; Cutolo, M.; Tyndall, A.; Müller-Ladner, U.; Matucci-
                                                                       Cerinic,  M.;  EUSTAR  Co-Workers.;  EUSTAR  Co-Workers.
           None.                                                       Preliminary  Analysis of the  Very Early Diagnosis of Systemic
                                                                       Sclerosis  (VEDOSS)  EUSTAR  Multicentre  Study:  Evidence  for
           Conflict of interest                                        Puffy Fingers as a Pivotal Sign for Suspicion of Systemic Sclerosis.
                                                                       Ann. Rheum. Dis., 2014, 73, 2087–93.
                                                                [7]    Kuryata, O.V.; Lysunets. T.K.; Semenov, V.V. Risk and Predictors
           The authors declare no conflicts of interests.              of Development of Arterial Hypertension in Patients with Systemic
                                                                       Sclerosis. Arterial Hypertens., 2017, 53, 17–22.
           Author contribution                                  [8]    Underwood, J.C.; Cross, S.S. Osteoarticular  and Connective
                                                                       Tissues. In: Hughes, D.E.; editor. General and Systematic Pathology.
                                                                       5  ed. Churchill Livingstone, Edinburgh, 2009. p710–474.
                                                                        th
           Conceptualization: Suleyman Serdar Koca              [9]    Agca, R.; Heslinga, S.C.; Rollefstad, S.; Heslinga, M.;
           Formal analysis: Mehdi Karasu                               McInnes,  I.B.;  Peters,  M.J.L.;  Kvien,  T.K.;  Dougados,  M.;
           Investigation: Mehdi Karasu, Ozkan Karaca                   Radner, H.; Atzeni, F.; Primdahl, J.; Södergren, A.; Jonsson, S.W.;
           Writing – original draft: Tarik Kivrak                      van Rompay, J.; Zabalan, C.; Pedersen,  T.R.; Jacobsson, L.;
           Writing – review & editing: Tarik Kivrak                    de  Vlam, K.; Gonzalez-Gay, M.A.; Semb,  A.G.; Kitas, G.D.;
                                                                       Smulders,  Y.M.; Szekanecz, Z.; Sattar, N.; Symmons, D.P.M.;
                                                                       Nurmohamed, M.T. EULAR Recommendations for Cardiovascular
                                                                       Disease Risk Management in Patients with Rheumatoid Arthritis
           Ethics approval and consent to participate                  and  Other  Forms  of  İnflammatory  Joint  Disorders:  2015/2016
           This study was approved by the Local Ethics                 Update. Ann. Rheum. Dis., 2017, 76, 17–28.
           Committee (218714).                                  [10]   Argula, R.G.; Harley. R.A.; Silver, R.M. Is Systemic Sclerosis-
                                                                       Related Pulmonary Arterial Hypertension a Distinct Phenotype? A
                                                                       Lung Morphometric Analysis of Systemic Sclerosis-Associated vs.
           Consent for publication                                     İdiopathic Pulmonary Arterial Hypertension. J. Scleroderma Relat.
                                                                       Disord., 2017, 2(suppl 1), s1–20.
           Consent for publication was obtained from all the    [11]    Condliffe, R.; Howard, L.S. Connective tissue disease-associated
                                                                       pulmonary arterial hypertension. F1000 Prime Cum, 2015, 7, 6.
           participants.                                        [12]    Condliffe, R.; Kiely, D.G.; Peacock, A.J.; Corris, P.A.; Gibbs, J.S.;
                                                                       Vrapi, F.;  et al. Connective tissue disease-associated pulmonary
           Availability of data                                        arter- ial hypertension in the modern treatment era. Am. J. Respir.
                                                                       Crit. Care Med., 2009, 179, 151–7.
           The data can be obtained following request from      [13]   Al-Mutari, N. Skin Diseases Seen in Diabetes Mellitus. Bull.
                                                                       Kuwait Inst. Med. Spec., 2006, 5, 30–9.
           the corresponding author.                            [14]   Pavlović,  M.D.;  Milenković,  T.;  Dinić,  M.;  Misović,  M.;
                                                                       Daković,  D.; Todorović, S.; Daković, Z.; Zecevi, R.D.; Doder, R.
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