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INNOSC Theranostics and
Pharmacological Sciences Management and maintenance of oral health

Funding https://doi.org/10.1016/j.ctrv.2018.06.007

None. 4. Yarom N, Shapiro CL, Peterson DE, et al., 2019, Medication-
related osteonecrosis of the jaw: MASCC/ISOO/ASCO
Conflict of interest Clinical practice guideline. J Clin Oncol, 37: 2270–2290.
https://doi.org/10.1200/JCO.19.01186
The authors declare that they have no competing interests.
5. Bonachea R, Katz J. 2022, Medication-related osteonecrosis
Author contributions of the jaw: A multifaceted diagnostic challenge. Mini review.
Am J Dent, 35: 109–112.
Conceptualization: Giovanna Mosaico
Formal analysis: Giovanna Mosaico 6. Campisi G, Mauceri R, Bertoldo F, et al., 2020, Medication-
Investigation: Giovanna Mosaico related osteonecrosis of jaws (MRONJ) prevention and
diagnosis: Italian consensus update 2020. Int J Environ Res
Methodology: Cinzia Casu Public Health, 17: 5998.
Writing – original draft: Giovanna Mosaico
Writing – review & editing: Cinzia Casu https://doi.org/10.3390/ijerph17165998
7. Kün-Darbois JD and Fauvel F, 2021, Medication-related
Ethics approval and consent to participate osteonecrosis and osteoradionecrosis of the jaws: Update
and current management. Morphologie, 105: 170–187.
Not applicable.
https://doi.org/10.1016/j.morpho.2020.11.008
Consent for publication 8. Hamadeh IS, Ngwa BA, Gong Y. 2015, Drug induced
Not applicable. osteonecrosis of the jaw. Cancer Treat Rev, 41: 455–464.
https://doi.org/10.1016/j.ctrv.2015.04.007
Availability of data
9. Fassio A, Bertoldo F, Idolazzi L, et al., 2017, Drug-induced
The document has been uploaded or deposited to a Qeios osteonecrosis of the jaw: The state of the art. Reumatismo,
preprint server ID: BGMWYJ, https://doi.org/10.32388/ 69: 9–15.
BGMWYJ. https://doi.org/10.4081/reumatismo.2017.983

Further disclosure 10. Seki K, Kaneko T, Kamimoto A, 2022, Medication-related
osteonecrosis of the jaw after tooth extraction in patients
Part or the entire set of results was presented at an ONJ receiving pharmaceutical treatment for osteoporosis:
(MRONJ) UPDATE 2021 conference on MAY 8 and 9, A retrospective cohort study. J Dent Sci, 17: 1619–1625.
2021, organized by the Piedmont-Valle D’aosta oncology https://doi.org/10.1016/j.jds.2022.03.014
network in Italy.
11. Yahara H, Hiraki A, Maruoka Y, et al., Shotgun metagenome
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