Page 64 - ITPS-7-4
P. 64
INNOSC Theranostics and
Pharmacological Sciences Drug repositioning for NTDs treatment
doi: 10.1017/S0031182017000993 31. Torreele E, Bourdin Trunz B, Tweats D, et al. Fexinidazole--a
new oral nitroimidazole drug candidate entering clinical
25. Sbaraglini ML, Vanrell MC, Bellera CL, et al. Neglected
tropical protozoan diseases: Drug repositioning as a rational development for the treatment of sleeping sickness. PLoS
option. Curr Top Med Chem. 2016;16(19):2201-2222. Negl Trop Dis. 2010;4(12):e923.
doi: 10.2174/1568026616666160216154309 doi: 10.1371/journal.pntd.0000923
26. Casulli A New global targets for NTDs in the WHO roadmap 32. FDA. The United States Food and Drug Administration;
2021-2030. PLoS Negl Trop Dis. 2021;15(5):e0009373. 2024. Available from: https://www.fda.gov/patients/learn-
about-drug-and-device-approvals/fast-track-breakthrough-
doi: 10.1371/journal.pntd.0009373 therapy-accelerated-approval-priority-review [Last accssed
27. Engels D, Zhou XN. Neglected tropical diseases: An effective on 2024 Oct 12].
global response to local poverty-related disease priorities. 33. EMA. European Medicines Agency; 2024. Available from:
Infect Dis Poverty. 2020;9(1):10. https://www.ema.europa.eu/en/human-regulatory-
doi: 10.1186/s40249-020-0630-9 overview/research-development/prime-priority-medicines
[Last accssed on 2024 Oct 12].
28. Begley CG, Ashton M, Baell J, et al. Drug repurposing:
Misconceptions, challenges, and opportunities for academic 34. Hernandez HW, Soeung M, Zorn KM, et al. High throughput
researchers. Sci Transl Med. 2021;13(612):eabd5524. and computational repurposing for neglected diseases.
Pharm Res. 2018;36(2):27.
doi: 10.1126/scitranslmed.abd5524
doi: 10.1007/s11095-018-2558-3
29. Weth FR, Hoggarth GB, Weth AF, et al. Unlocking hidden
potential: Advancements, approaches, and obstacles 35. A Global Network for Neglected Tropical Diseases; 2024.
in repurposing drugs for cancer therapy. Br J Cancer. Available from: https://ntd-network.org [Last accssed on
2023;130:703-715. 2024 Oct 12].
doi: 10.1038/s41416-023-02502-9 36. Uniting to Combat NTDs; 2024. Available from: https://
unitingtocombatntds.org [Last accssed on 2024 Oct 12].
30. Ma Z, Augustijn K, De Esch I, Bossink B. Public-private
partnerships influencing the initiation and duration of 37. Médecins Sans Frontières; 2024. Available from: https://www.
clinical trials for neglected tropical diseases. PLoS Negl Trop msf.org [Last accssed on 2024 Oct 12].
Dis. 2023;17(11):e0011760.
38. Bill & Melinda Gates Foundation; 2024. Available from: https://
doi: 10.1371/journal.pntd.0011760 www.gatesfoundation.org [Last accssed on 2024 Oct 12].
Volume 7 Issue 4 (2024) 8 doi: 10.36922/itps.3721

