Page 21 - JCBP-1-1

Journal of Clinical and
Basic Psychosomatics Smoking and schizophrenia symptoms

Table 1. (Continued)
Study Goal of study Main relevant results
Does smoking reduce akathisia? Testing a narrow Examined whether heavy smoking The self-medication theory does
version of the self-medication hypothesis [52] reduces akathisia. not explain the elevated rates of
smoking observed in individuals
with SCZ.
Cognitive performance and smoking in first-episode Examined the differences in the course of Smoking may improve attention.
psychosis: The self-medication hypothesis [25] those deficits after APs.
SCZ and smoking: An epidemiological survey in a state Determined whether smoking is related The relationship between high
hospital [48] to SCZ. doses of neuroleptics and smoking
was observed only in patients
without SCZ.
Preservation effect: Cigarette smoking acts on the The study aimed to determine if smoking The investigation of neural
dynamic of influences among unifying neuropsychiatric could improve the dynamics of networks pathways can yield novel insights
triple networks in SCZ [53] in individuals with SCZ. into the self-medication hypothesis
in SCZ.
Higher rates of cigarette smoking in male adolescents Investigated the prevalence of cigarette Based on data indicating
before the onset of SCZ: A historical-prospective cohort smoking in adolescents later hospitalized abnormalities in nicotinic
study [54] for SCZ. transmission in patients with
SCZ and their relatives, a higher
prevalence of smoking among
individuals who will later
develop SCZ before the onset
of the illness could suggest a
link between impaired nicotinic
neurotransmission and SCZ.
Psychoactive substance use in specialized psychiatric Investigated prevalence and correlates of Patients with SCZ were more often
care patients [55] substance use among patients. daily smokers.
Smoking improves divided attention in SCZ [23] Examined the interactional effects of SCZ The positive effect of smoking on
and smoking history on divided attention. divided attention.
Health for smokers with SCZ — a struggle to maintain a Investigated the habits of smokers with Smokers with SCZ experience
dignified life [56] SCZ and smoking in relation to health. health problems.
Effects of tobacco on AP treatments and their symptoms Evaluated the prevalence of tobacco in SCZ patients smoke for reasons
in SCZ [32] patients with SCZ and test if smoking other than reducing psychotic or
reduces psychotic and extrapyramidal extrapyramidal symptoms.
symptoms.
Smoking and cognitive deficits in SCZ: A pilot study [42] Among the smokers, the number of Smoking may alleviate cognitive
cigarettes smoked per day was associated deficits in SCZ by increasing
with the severity of cognitive symptoms. dopaminergic neurotransmission.
Tobacco and cognitive performance in SCZ patients: The Described the methodology used in the The high rates of tobacco use in
design of the COGNICO study [57] COGNICO study. patients with mental disorders.
Nicotine use and its correlates in patients with At the beginning of the study and An interpretation of the findings
psychosis [58] annually for 5 years, levels of nicotine is that patients with psychosis fail
usage were assessed in addition to other to desist from nicotine rather than
pertinent ratings and measurements. experience the positive effects of
the usage.
Differential sensory gating functions between smokers The effects of cigarette smoking, without Support a sensory gating deficit
and non-smokers among drug-naive first-episode new acute exposure before testing, on among first-episode SCZ patients.
schizophrenic patients [26] sensory gating using the P50 auditory It was less pronounced among
evoked potential in a group of SCZ SCZ patients who were cigarette
smokers and healthy smokers. smokers.
Separate and combined effects of low-dose ketamine and Investigated the separate and interactive Acute alterations and individual
nicotine on behavioral and neural correlates of sustained roles of the N-methyl-d-aspartate differences in nAChR function can
attention [59] receptor and nAChR systems in the moderate glutamatergic-driven
modulation of attention. cognitive deficiencies in SCZ.
(Cont’d...)

Volume 1 Issue 1 (2023) 4 https://doi.org/10.36922/jcbp.1014