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Journal of Clinical and
            Basic Psychosomatics                                            Crouzon comorbidity with psychiatric disorders



            departments specializing in the oral cavity, plastic surgery,
            otolaryngology, or ophthalmology. Seeking medical
            attention in the psychiatry department, like in the present
            case, is rare. Taylor and Bartlett proposed that mental
            health should be given great importance throughout the
                                   [6]
            treatment of patients with CS .
            2. Case presentation
            2.1. Medical history
            A 15-year-old girl was brought in by her mother and
            admitted to the department of psychiatry for treatment
            on November 9, 2022. She had visited the local outpatient
            clinic with limited improvement. Her parents reported
            that she was positive before Grade  4 of primary school.   Figure 1. Physical examination: scaphocephaly (“scaphocephalic” skull
                                                               shape), exophthalmos (prominent eyeballs), beaked nose, facial anomalies
            Since junior high school, she often felt unhappy due to   with hypoplastic maxilla, and relative mandibular prognathism.
            her appearance and poor interpersonal relationships. In
            addition, she rarely spoke to others, resulting in an intense   tension in the limbs increased with passive posture without
            relationship. She experienced full-term normal delivery,   active resistance.
            and her brother did not report similar medical issues. Her
            academic performance remained at an average level.  2.4. Laboratory examination

            2.2. Mental status examination                     A suspicion of CS was raised, and imaging examinations
                                                               were requested. The results revealed the following:
            The girl harmed herself with her nails when experiencing
            an unstable mood. She was anhedonia and refused to   (i).  Imaging examinations: A head computed tomography
            complete homework 7 days before the visit. She insisted that   (CT) showed a “hammered silver” (beaten metal/
            someone had drugged her in a glass of water and argued   copper  beaten)  pattern,  once  regarded  as  a  marker
            that it was from her classmates. Her mother, who worked in   of increased intracranial pressure (Figure 2A). Spinal
            a private pharmacy, treated her with “Promethazine 18mg”   dysplasia was also indicated in the CT report. Besides,
            to help her sleep without an appropriate subscription.   a head MRI showed the widening of the anterior brain
            She was able to fall asleep after the injection. Her parents   pool in the left temporal lobe without excluding a
            claimed she repeatedly spoke single words, such as “mom”   small arachnid cyst and leftward deviation of the nasal
            and “dad.”                                            septum (Figure 2B-F).
                                                               (ii). Psychological examinations: Psychiatric examination
              Fear, nervousness, and the urge to walk outside were   indicated that infrared thermal imaging examination
            presented in her during the visit to the local hospital on   prompted mildly abnormal cerebral blood flow activity;
            November  4.  The  following  day,  she  would  not  talk  or   mental stress analysis showed the level of fatigue and
            eat at all. She was given oral medications (lorazepam and   psychological  stress  was  normal,  but  the  activity  of
            olanzapine, at a dosage of 2.5 mg/night) for about 1 week,   the autonomic nerve was relatively strong; event-
            but the improvement was poor.                         related potential (ERP) showed mild abnormalities
                                                                  in  attention  and  immediate  memory;  the  scores  of
            2.3. Physical examination
                                                                  extraversion (E), neuroticism (N), psychoticism (P),
            On the day of admission, the head examination showed   and validity (L) in Eysenck Personality Questionnaire
            scaphocephaly (“scaphocephalic” skull shape), and the   (standard score) were 10, 50, 35, and 50, respectively;
            head circumference was 54 cm. The physical examination   electroencephalography  (EEG)  indicated  that
            showed that normal height (147 cm), weight (35 kg), and   subthreshold electroencephalogram occurred. There
            body  mass index (16.2  kg/m )  were comparable to the   were no obvious abnormalities in the suicidal ideation
                                    2
            children of the same age. The patient was stupor at the time   self-assessed test and intellectual development.
            of examination, presented with physical facial features such   (iii). Others: Electrocardiogram revealed sinus arrhythmia;
            as exophthalmos (prominent eyeballs), hypertelorism,   polysomnography suggested no indication of sleep
            hypopsia, beaked nose, facial anomalies with hypoplastic   apnea syndrome; ophthalmologic examination showed
            maxilla, and relative mandibular prognathism (Figure 1).   that the actual visual acuity based on international
            The subsequent examination revealed that the muscle   standard vision  chart was 0.12 for the right eye


            Volume 1 Issue 1 (2023)                         2                        https://doi.org/10.36922/jcbp.0405
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